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ProteomicsiTRAQ proteomics of sentinel lymph nodes for the identification of extra cellular matrix protein signatures that can flag metastasis in early breast cancer
Background Breast cancer patients who present in the early stage of disease are affected by metastasis to the axillary group of lymph nodes. The first among this group that is affected is called as sentinel lymph node, and metastasis to this lymph node is crucial for the staging of cancer and the qu...
ORGANISM(S): Homo sapiens (Human) 
2022-05-01 | PXD027668 | Pride
Itraq proteomics Extracellular matrix proteins Early breast cancer Sentinel lymph node metastasis 
GenomicsBreast Cancer Remodels Lymphatics in Sentinel Lymph Nodes
Breast Cancer Remodels Lymphatics in Sentinel Lymph Nodes
PRJNA1271534 | ENA
ProteomicsImmunoproteomics of Lymph Node T-cells in Bladder Cancer
The immune-suppressive features often possessed by invasive tumors hamper effective anti-tumor immunity. In this context, tumor-infiltrating regulatory T cells (Tregs) have been widely implied, principally as unwanted suppressors of anti-tumor immune responses. However, while many studies have focus...
ORGANISM(S): Homo sapiens (Human) 
2020-09-09 | PXD009569 | Pride
Human Lymph nodes T-cells Cancer 
GenomicsBreast cancer remodels lymphatics in sentinel lymph nodes
Breast cancer remodels lymphatics in sentinel lymph nodes
PRJNA1042832 | ENA
TranscriptomicsTranscription profiling of human lymph node (sinuses) and tonsil (no sinuses) to identify signature genes that are prime candidates for mediating adhesion of tumor cells to sinusoidal cells
Lymph node vs. tonsil
ORGANISM(S): Homo sapiens 
2007-09-12 | E-GEOD-2665 | biostudies-arrayexpress
ProteomicsSentinel Lymph Node and Endometrial Cancer Grade in depth Proteomic Analyses : A Novel Approach for Molecular Diagnosis
Endometrial cancer is the most common gynecological cancer worldwide. In women from developed countries, endometrial cancer is usually detected after the age of 60 years. Nearly 90% of the diagnosed cases are sporadic, while 10% are attributed to genetic factors. Thus, it is necessary to develop a d...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD020410 | Pride
Ghost proteome Endometrial cancer Proteomic Diagnosis Sentinel lymph nodes Protein mutations Small prot 
ProteomicsSoluble lymph node proteome during anthrax infection in mice
This study aimed to characterize a soluble proteome of popliteal lymph nodes during lymphadenitis induced by intradermal injection of Bacillus anthracis Sterne spores in mice using tandem LC-MS/MS. More than 380 proteins were detected in the normal intra-nodal lymph, while the infectious process res...
ORGANISM(S): Mus musculus (Mouse) 
2014-10-21 | PXD001342 | Pride
Lymph Anthrax Mice Lymph node Proteome 
TranscriptomicsGene expression profiles of mouse sentinel lymph nodes (SLNs) in xenotransplanted and non tumor bearing CB17 SCID.
Cutaneous melanoma first metastasizes into sentinel lymph nodes that control the lymphatic drain from the area of the primary tumor. This observation is used clinically for melanoma patients with primary melanomas thicker than 1mm (tumor stage ≥T2a), for these patients sentinel lymph node biopsy has...
ORGANISM(S): Mus musculus 
2011-07-14 | E-GEOD-30688 | biostudies-arrayexpress
GenomicsBreast cancer remodels lymphatics in sentinel lymph nodes
Breast cancer remodels lymphatics in sentinel lymph nodes
PRJNA1041730 | ENA
TranscriptomicsGene expression profiles of mouse sentinel lymph nodes (SLNs) in xenotransplanted and non tumor bearing CB17 SCID.
Cutaneous melanoma first metastasizes into sentinel lymph nodes that control the lymphatic drain from the area of the primary tumor. This observation is used clinically for melanoma patients with primary melanomas thicker than 1mm (tumor stage ≥T2a), for these patients sentinel lymph node biopsy has...
ORGANISM(S): Mus musculus 
2011-07-15 | GSE30688 | GEO
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