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TranscriptomicsTranscription profiling of human HMVEC cells treated with vascular endothelial growth factor, anthrax edema toxin, and an Epac activator
Human microvascular endothelial cells (HMVEC) treated with vascular endothelial growth factor (VEGF), Antrhax Edema Toxin (ET), or the Epac activator, 8-pCPT-2'-O-Me-cAMP (8CPT); Human microvascular endothelial cells (HMVEC) were treated with VEGF alone or VEGF in combination with either the the Epa...
ORGANISM(S): Homo sapiens 
2009-09-13 | E-GEOD-17777 | biostudies-arrayexpress
GenomicsAnthrax anthrax
Anthrax anthrax overview
PRJNA1084976 | ENA
ProteomicsDiscovery of Mouse Spleen Signaling Responses to Anthrax using Label-Free Quantitative Phosphoproteomics via Mass Spectrometry
From article abstract: Inhalational anthrax is caused by spores of the bacterium Bacillus anthracis (B. anthracis), and is an extremely dangerous disease that can kill unvaccinated victims within 2 weeks. Modern antibiotic-based therapy can increase the survival rate to ~50%, but only if administere...
ORGANISM(S): Bacillus anthracis str. Sterne Mus musculus (Mouse) 
2017-03-22 | PXD006148 | Pride
Lc-msms Phosphoproteomics Mouse Label-free Spleen Anthrax 
ProteomicsSoluble lymph node proteome during anthrax infection in mice
This study aimed to characterize a soluble proteome of popliteal lymph nodes during lymphadenitis induced by intradermal injection of Bacillus anthracis Sterne spores in mice using tandem LC-MS/MS. More than 380 proteins were detected in the normal intra-nodal lymph, while the infectious process res...
ORGANISM(S): Mus musculus (Mouse) 
2014-10-21 | PXD001342 | Pride
Lymph Anthrax Mice Lymph node Proteome 
TranscriptomicsActivity of the Bacillus anthracis 20 kDa protective antigen component
Edema factor of anthrax binds to the protective antigen (PA83) which cleaves to PA63 and PA20. The role of PA20 was examined using highthroughput gene expression analysis of human peripheral blood mononuclear cells (PBMC) exposed to PA20. Keywords: Toxicity determination PBMC obtained from differe...
ORGANISM(S): Homo sapiens 
2008-08-26 | E-GEOD-12533 | biostudies-arrayexpress
GenomicsidAntAnth
Anthrax anthrax (the anthracite bee-fly)
PRJEB64720 | ENA
TranscriptomicsTranscription profiling of murine macrophage-like RAW 264.7 cells treated with EdTx, protective antigen, or LPS for different length of time to examine the effect of EdTx on global transcriptional profiles.
Edema toxin (EdTx), which is a combination of edema factor and a binding moiety (protective antigen), is produced by Bacillus anthracis, the etiological agent of anthrax. EdTx is an adenylyl cyclase enzyme that converts adenosine triphosphate to adenosine-3',5'-monophosphate, resulting in interstiti...
ORGANISM(S): Mus musculus 
2007-11-22 | E-GEOD-4712 | biostudies-arrayexpress
GenomicsidAntAnth1
Anthrax anthrax (the anthracite bee-fly) genome assembly, idAntAnth1
PRJEB73461 | ENA
GenomicsidAntAnth
Anthrax anthrax (the anthracite bee-fly), genomic and transcriptomic data
PRJEB64719 | ENA
GenomicsidAntAnth1 alternate haplotype
Anthrax anthrax (the anthracite bee-fly) genome assembly, idAntAnth1, alternate haplotype
PRJEB73462 | ENA
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