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MetabolomicsPharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock
Not available
ORGANISM(S): Homo sapiens 
ST000785 | MetabolomicsWorkbench
TranscriptomicsExpression data for derivation of septic shock subgroups
Background: Septic shock is a heterogeneous syndrome within which probably exist several biological subclasses. Discovery and identification of septic shock subclasses could provide the foundation for the design of more specifically targeted therapies. Herein we tested the hypothesis that pediatric...
ORGANISM(S): Homo sapiens 
2011-01-13 | E-GEOD-26440 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human pediatric septic shock samples to validation of previous experiment
Rationale: We previously generated genome-wide expression data in children with septic shock, based on whole blood-derive RNA, having the potential to lead the field into novel areas of investigation. Objective: Herein we seek to validate our data through a bioinformatic approach centered on a val...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-9692 | biostudies-arrayexpress
TranscriptomicsGenome wide transcriptomic experiments: gene counts for whole blood RNA-Seq from children with septic shock at PICU admission (TP1) and 48 hours later (TP2)
Gene Expression Analysis for Modelling Immune Trajectory and Endotype Transition During Pediatric Septic Shock We aimed to characterise the immune trajectory of 19 children with septic shock from first interaction with pediatric critical care teams (TP1) to 48 hours afterwards (TP2). We analysed da...
ORGANISM(S): Homo sapiens 
2026-09-05 | E-MTAB-17576 | biostudies-arrayexpress
ProteomicsRCL glycosylation of serum corticosteroid-binding globulin: implications in cortisol delivery and septic shock
Corticosteroid-binding globulin (CBG) is a serum glycoprotein that binds and delivers anti-inflammatory cortisol to inflammatory sites through neutrophil elastase (NE)-mediated proteolysis of an exposed reactive centre loop (RCL) on CBG. Timely and tissue-specific delivery of cortisol is critical to...
ORGANISM(S): Homo sapiens (Human) 
2025-03-07 | PXD058963 | Pride
Human serum Septic shock O-glycosylation Lc-ms/ms 
TranscriptomicsTranscription profiling of human SIRS and septic shock patients reveals
Goal of the experiment: To identify correlated genes, pathways and groups of patients with systemic inflammatory response syndrome and septic shock that is indicative of biologically important processes active in these patients. Background: We measured gene expression levels and profiles of childr...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4607 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human whole blood from pediatric septic shock patients
In an ongoing translational research program involving microarray-based expression profiles in pediatric septic shock, we have now conducted longitudinal studies focused on the temporal expression profiles of canonical signaling pathways and gene networks. Genome-level expression profiles were gener...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8121 | biostudies-arrayexpress
ProteomicsPolymorphonuclears in septic shock
Proteome analysis of polymorphonuclear cells isolated from patients suffering with septic shock.
ORGANISM(S): Homo Sapiens (human) 
2021-10-21 | PXD029219 | JPOST Repository
GenomicsGene expression patterns in septic and non-septic shock postsurgical patients
Gene expression patterns in septic and non-septic shock postsurgical patients
PRJNA544706 | ENA
ProteomicsQuantitative analysis of the global proteome of heart tissue in septic shock
Nowadays, sepsis and septic shock have become major public health problems, which are the main cause of death among patients admitted to the intensive care units. Notably, myocardial dysfunction during sepsis, usually called sepsis-induced myocardial depression, is common in septic shock patients wh...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-19 | PXD029649 | Pride
Shock Sepsis Proteome Myocardial depression 
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