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MetabolomicsIdentification of Biomarkers using Metabolomics in Porcine Hemorrhagic Shock
Hemorrhagic shock with injury results in alterations of the metabolic state of an organism, which contribute to organ dysfunction and death. Previous investigations have explored the effects of carbohydrate prefeed in murine models but few in clinically relevant large animal models. We performed car...
2015-01-31 | MTBLS123 | MetaboLights
MetabolomicsA multi-omics dataset of heat-shock response in the yeast RNA binding protein Mip6 (NMR assay)

Gene expression is a biological process regulated at different molecular levels, including chromatin accessibility, transcription, and RNA maturation and transport. In addition, these regulatory mechanisms have strong links with cellular metabolism. Here we present a multi-omics dataset that capt...

2020-02-14 | MTBLS1320 | MetaboLights
MetabolomicsDifferentiating Hemorrhagic Shock and Organophosphate Poisoning through Integrated Skin Microbiome–Metabolome Signatures

Accurate determination of cause of death and estimation of postmortem interval (PMI) are critical yet challenging tasks in forensic science, particularly in cases with rapid demise and minimal gross findings. We employed an integrative multi-omics approach to characterize postmortem microbial suc...

2026-06-01 | MTBLS14219 | MetaboLights
MetabolomicsDecoding heat-shock responses in Vitis vinifera L. by metabolic, VOC and physiological profiling: towards the identification of volatile and metabolic biomarkers

Grapevine (Vitis spp.) is a crop of major economic importance in Europe. Rising temperatures and extreme weather events reduce yield and alter berry composition, affecting wine quality. Despite advances in vineyard management, mechanisms underlying grapevine thermotolerance remain poorly understo...

2026-06-26 | MTBLS13195 | MetaboLights
MetabolomicsPharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock
Not available
ORGANISM(S): Homo sapiens 
ST000785 | MetabolomicsWorkbench
TranscriptomicsTransient Genotype-by-Environment Interactions in the Yeast Genomic Expression Response to Heat Shock
Microarray time courses followed the response of 5 yeast strains to heat shock. Expression variation due to genetic, environmental, and genotype-by-environment interactions were identified. Keywords: Timecourse and single timepoint expression studies of stress response in yeast The genomic express...
ORGANISM(S): Saccharomyces cerevisiae 
2010-05-18 | E-GEOD-15147 | biostudies-arrayexpress
TranscriptomicsWidespread regulation of translation by elongation pausing in heat shock
RNA-seq and ribosome footprinting libraries of mouse 3T3 and human 293T cellsrelated to Shalgi et al. 2013 36bases paired-end RNA-seq, and ribosome footprinting libraries for: 3T3 cells - Control, 8 hours of mild heat shock (42) and 2 hours of severe heat shock (44) - in replicates, as well as 3T3 ...
ORGANISM(S): Mus musculus 
2013-01-03 | E-GEOD-32060 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of recombinant E. coli to heat-shock and dual heat-shock recombinant protein induction
Recombinant Escherichia coli cultures are used to manufacture numerous therapeutic proteins and industrial enzymes, where many of these processes use elevated temperatures to induce recombinant protein production. The heat-shock response in wild-type E. coli has been well studied. In this study, t...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17507 | biostudies-arrayexpress
TranscriptomicsHeat shock: genomic run-on (GRO) analysis
This SuperSeries is composed of the following subset Series: GSE24483: TR heat-shock GSE24484: RA heat-shock Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
2011-04-19 | E-GEOD-24488 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of Escherichia coli O157:H7 EDL933 during heat shock using microarrays
The transcriptome of Escherichia coli K-12 has been widely studied over a variety of conditions for the past decade while such studies involving E. coli O157:H7, its pathogenic cousin, are just now being conducted. To better understand the impact of heat shock on E. coli O157:H7, global transcript l...
ORGANISM(S): Escherichia coli 
2009-04-01 | E-GEOD-11463 | biostudies-arrayexpress
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