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ProteomicsInhibition of melanization activation by Serpin-5 and Serpin-9 promotes nucleopolyhedrovirus infection in cotton bollworm Helicoverpa armigera
One of important insect defense mechanisms is melanization, which are mediated by clip domain serine protease (cSP) cascades and regulated by Serpins. In vitro, activation of melanization can efficiently kill Nucleopolyhedrovirus (NPV). However, quantitative proteomics revealed that the infection of...
ORGANISM(S): Helicoverpa armigera (Cotton bollworm) 
2017-09-19 | PXD006126 | Pride
Prophenoloxidase Hemolymph Cotton bollworm Serpin Melanization 
ProteomicsSerpin, Cystatin as Novel Correlates of HIV-1 Resistance in the Cervicovaginal Mucosa of Sex Workers
Not available
2013-11-23 | MSV000078506 | MassIVE
GenomicsLoss of Serpin E2 alters antimicrobial gene expression by microglia but not astrocytes
Loss of Serpin E2 alters antimicrobial gene expression by microglia but not astrocytes
PRJNA939500 | ENA
UnknownSERPIN-Derived Small Peptide (SP16) as a Potential Therapeutic Agent against HIV-Induced Inflammatory Molecules and Viral Replication in Cells of the Central Nervous System.
Not available
S-EPMC9954444 | biostudies-literature
TranscriptomicsA serpin, SAS1, controls hormonal cross talk in the plant defense pathway
A possible regulatory role for SAS1 was evaluated by examining gene expression patterns of SAS1-HA plants. Keywords: serpin overexpression
ORGANISM(S): Arabidopsis thaliana 
2008-03-10 | GSE3246 | GEO
ProteomicsThe Serpin-like Loop-insertion of Ovalbumin Increases Stability and Reduces OVA 323-339 Epitope Immunogenicity
Chicken ovalbumin (cOVA) has been studied for decades primarily due to the robust genetic and molecular resources that are available for experimental investigations. cOVA is a member of the serpin superfamily of proteins that function as protease inhibitors, although cOVA does not exhibit this activ...
ORGANISM(S): Gallus gallus (Chicken) 
2021-05-07 | PXD021756 | Pride
Lc-ms Antigen processing Limited proteolysis 
UnknownAnalysis of mutually exclusive alternatively spliced serpin-1 isoforms and identification of serpin-1 proteinase complexes in Manduca sexta hemolymph.
Not available
S-EPMC2937995 | biostudies-literature
GenomicsGenome-wide analysis of gene expression from islets of different sizes in response to in vivo serpin B13 mAB treatment
Genome-wide analysis of gene expression from islets of different sizes in response to in vivo serpin B13 mAB treatment
PRJNA515333 | ENA
TranscriptomicsLoss of Serpin E2 alters antimicrobial gene expression by microglia but not astrocytes
To investigate the influence of Serpin E2 (aka PN-1) on glia in the brain, we purified microglia and astrocytes and performed RNA sequencing from Serpine2-/- mice
ORGANISM(S): Mus musculus 
2026-02-02 | GSE226269 | GEO
UnknownInhibition of melanization by serpin-5 and serpin-9 promotes baculovirus infection in cotton bollworm Helicoverpa armigera.
Not available
S-EPMC5633200 | biostudies-literature
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