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MetabolomicsDissection of two routes to naïve pluripotency using different kinase inhibitors
Embryonic stem cells (ESCs) can be maintained in the naïve state through inhibition of Mek1/2 and Gsk3 (2i). A relevant effect of 2i is the inhibition of Cdk8/19, which are negative regulators of the Mediator complex, responsible for the activity of enhancers. Inhibition of Cdk8/19 (Cdk8/19i) stimul...
2021-02-10 | MTBLS301 | MetaboLights
UnknownSynergetic adsorption-photocatalysis process for water treatment using TiO2 supported on waste stainless steel slag.
Not available
S-EPMC9120099 | biostudies-literature
UnknownTranscriptomic Analysis Reveals the Wound Healing Activity of Mussel Myticin C.
Not available
S-EPMC7023338 | biostudies-literature
UnknownEffect of BCG Revaccination on Occupationally Exposed Medical Personnel Vaccinated against SARS-CoV-2.
Not available
S-EPMC8617982 | biostudies-literature
UnknownInjectable Gel Form of a Decellularized Bladder Induces Adipose-Derived Stem Cell Differentiation into Smooth Muscle Cells In Vitro.
Not available
S-EPMC7696281 | biostudies-literature
ProteomicsSenescent cells display an altered immunopeptidome and promote CD8-dependent antitumor immunity
Cellular senescence is a stress response known to activate innate immunity. However, how senescent cells interact with the adaptive immune system remains largely unexplored. Here, we show that senescent cells display an enhanced MHC class I antigen processing and presentation. Furthermore, senescent...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2022-10-18 | PXD033714 | Pride
Senescence Plasma membrane 
UnknownThe percentage of CD39+ monocytes is higher in pregnant COVID-19+ patients than in nonpregnant COVID-19+ patients.
Not available
S-EPMC9333267 | biostudies-literature
ProteomicsVenom proteomics of the Amazonian spider Acanthoscurria juruenicola
Acanthoscurria juruenicola is an Amazonian tarantula spider described for the first time a century ago. Specimens of both genders are similar in size and in most morphological aspects, but ecological behavior and their venom composition remained unknown to date. Here we present the trascriptomics, p...
ORGANISM(S): Acanthoscurria Juruenicola 
2021-07-08 | MSV000087777 | MassIVE
ProteomicsHsa-miR-139-5p expression regulates the abundance of proteins related to poor survival cancer in CAL-62 thyroid cancer cell line
We studied the impact of hsa-miR-139-5p on the protein output by means of an iTRAQ-based approach. First, we established two CAL-62 isogenic cell lines expressing either the mature hsa-miR-139-5p or a non-targeting control upon a doxycycline inducible promoter (PTRE3G-tGFP, Dharmacon). Total protein...
ORGANISM(S): Homo sapiens (Human) 
2019-08-13 | PXD011901 | Pride
Thyroid cancer Cal-62 Hsa-mir-139-5p Impact Itraq 
ProteomicsDefective Olfactomedin-2 connects adipocyte dysfunction to obesity
Olfactomedin-2 (OLFM2) is a pleiotropic glycoprotein emerging as a regulator of energy homeostasis. We here show the expression of OLFM2 to be adipocyte-specific and inversely associated with obesity. OLFM2 levels increase during adipocyte differentiation and are suppressed in inflamed adipocytes. F...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2025-06-24 | MSV000098300 | MassIVE
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