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MetabolomicsUntargeted metabolomic analysis of lamb serum
Using untargeted metabolomics to investigate the effects of different supplementation routes on serum metabolites in lambs
2026-08-05 | MTBLS14325 | MetaboLights
Metabolomics1H-NMR-based metabolomic analysis identifies disrupted glutamate metabolism as distinct serum signature in Parkinson’s disease patients
Using High-Performance Liquid Chromatography, we recently demonstrated a complex dysregulation of the glutamate NMDA receptor-stimulating amino acids in the brain, CSF and serum of Parkinson’s disease (PD) experimental models and patients. Here, we investigate the serum metabolomic profile in the sa...
2024-11-08 | MTBLS10958 | MetaboLights
MetabolomicsSerum metabolomics analysis of patients with chronic obstructive pulmonary disease and 'frequent exacerbator' phenotype

BACKGROUND: Chronic obstructive pulmonary disease (COPD) exacerbations significantly contribute to morbidity and mortality. The complex nature of COPD presents challenges in accurately predicting and understanding frequent exacerbations.

OBJECTIVE: This stu...

2024-02-23 | MTBLS9119 | MetaboLights
MetabolomicsSerum and Fecal Metabolomics Analysis in Laboratory-Kenneled Poodles

This study was conducted to investigate the effects of Lycium barbarum polysaccharides and glycopeptide on the serum and metabolomics of laboratory-kenneled Poodles.

2026-03-12 | MTBLS14033 | MetaboLights
MetabolomicsRat serum transcriptomic data

study investigated the anti-fatigue effect of the Panax ginseng–Astragali Radix (GGJ) herb pair, the core functional unit of Baoyuan Decoction, using a rat fatigue model induced by forced swimming. Serum samples were collected for untargeted metabolomics analysis by LC-MS/MS to profile differenti...

2026-06-30 | MTBLS14902 | MetaboLights
Metabolomicstargeted metabolomics of rat's serum
Podophyllotoxin (PPT) exhibits limited clinical utility due to its nephrotoxicity, and its underlying mechanisms remain poorly understood. This study employs the toxicological evidence chain (TEC) framework and integrated multi-omics analyses to investigate the potential involvement of the microbiot...
2026-06-27 | MTBLS14868 | MetaboLights
MetabolomicsMulti-Omics Analysis Reveals Disturbance of Nanosecond Pulsed Electric Field in the Serum Metabolic Spectrum and Gut Microbiota

Nanosecond pulsed electric field (nsPEF) is a novel ablation technique that based on high-intensity electric voltage to achieve tumor-killing effect in the target region, and increasingly considered for treating tumours of the liver, kidneys, and other organs with rich blood supply. When we were ...

2021-06-21 | MTBLS2406 | MetaboLights
MetabolomicsIntegrated analysis of faecal microbial diversity and serum metabolome reveals the profiling of gut microbiota-related metabolites in rats and mice prolonged exposure to environmental high humidity

Background: High humidity, as a key climate risk factor, has become one of the significant threats to public health. However, less is known about the mechanism by which the high humidity environment affects the health of the population. The present study was designed to reveal the profile of gut ...

2026-06-16 | MTBLS5653 | MetaboLights
MetabolomicsA Cross-Platform Metabolomics Comparison Identifies Serum Metabolite Signatures of Liver Fibrosis Progression in Chronic Hepatitis C Patients
Metabolomics offers new insights into disease mechanisms that is enhanced when adopting orthogonal instrumental platforms to expand metabolome coverage, while also reducing false discoveries by independent replication. Herein, we report the first inter-method comparison when using multisegment injec...
2023-08-22 | MTBLS3111 | MetaboLights
MetabolomicsIntegrated analysis of faecal microbial diversity and serum metabolome reveals the profiling of gut microbiota-related metabolites in rats and mice prolonged exposure to environmental high humidity

Background: High humidity, as a key climate risk factor, has become one of the significant threats to public health. However, less is known about the mechanism by which the high humidity environment affects the health of the population. The present study was designed to reveal the profile of gut ...

2026-06-16 | MTBLS5660 | MetaboLights
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