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ProteomicsKidney disease proteome research
The study included 75 participants, among whom 51 patients were diagnosed with kidney diseases: Calculus of kidney (N20.0, URCD) and Cyst of kidney (N28.1, ACDK), Malignant neoplasm of kidney, except renal pelvis (С64, RNCL) and 24 conditionally healthy participants (CNTR).
ORGANISM(S): Homo sapiens (Human) 
2025-01-07 | PXD051799 | Pride
Kidney diseases Protein analysis Tandem mass spectrometry Plasma Kidney cancer Protein phosphorylation Human 
TranscriptomicsSingle-cell RNA-Seq of bovine macrophage cell lines from two cow strains infected with Theileria
To understand the immune response of cows to the apicomplexan parasite Theileria annulata, we used ex vivo isolate cells derived from two infected calve : Holstein 12886 (Bos taurus), which is known to be susceptible to the disease, and Sahiwal 82H (Bos indicus), which is known to be resistant. The ...
ORGANISM(S): Bos taurus 
2024-10-09 | E-MTAB-14450 | biostudies-arrayexpress
ProteomicsMyokines in gastric cancer cachexia
In this study, we sought to explore the importance of selected myokines in a homogenous population of patients with gastric cancer characterized by high rates of Cancer-Associated Cachexia [CAC]. Myokine levels in peripheral blood were compared between patients with and without cachexia to identify ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049334 | Pride
Proteomics Mass spectrometry Gastric cancer Cachexia Myokines 
UnknownKnapsack--TOPSIS Technique for Vertical Handover in Heterogeneous Wireless Network.
Not available
S-EPMC4523173 | biostudies-literature
TranscriptomicsMPA and NQO studies (Sevilla)
RNA polymerases deal with obstacles during transcription elongation that need to be removed. One important type of hindrance consists of DNA lesions, which are removed by transcription-coupled repair (TCR). To improve our knowledge of transcription elongation and its coupling to TCR, we performed DN...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-29 | E-GEOD-11561 | biostudies-arrayexpress
MetabolomicsSMN deficiency perturbs monoamine neurotransmitter metabolism in spinal muscular atrophy

Beyond motor neuron degeneration, homozygous mutations in the survival motor neuron 1 (SMN1) gene cause multiorgan and metabolic defects in patients with spinal muscular atrophy (SMA). However, the precise biochemical features of these alterations and the age of onset in the brain and peripheral ...

2023-11-27 | MTBLS8784 | MetaboLights
UnknownComparative molecular docking analysis of essential oil constituents as elastase inhibitors.
Not available
S-EPMC3374355 | biostudies-literature
UnknownUnstressed cells are alike, but stressed cells differ: Environmental and single-cell heterogeneity in yeast stress responses.
Not available
S-EPMC12803069 | biostudies-literature
ProteomicsDownregulation of Human-Specific lncRNA TMEM9B-AS1 in Skeletal Muscle of People with Type 2 Diabetes Impacts Ribosomal Biogenesis
Long non-coding RNAs (lncRNAs) are important regulators of skeletal muscle physiology, with altered expression noted in several human diseases including type 2 diabetes. Here we report downregulation of TMEM9B-AS1, a previously uncharacterized lncRNA, in skeletal muscle of men with type 2 diabetes. ...
ORGANISM(S): Homo sapiens (Human) 
2025-04-22 | PXD053490 | Pride
Lc-ms/ms Lncrna interactors Rna-binding proteins 
UnknownRobust Prediction of Enzyme Variant Kinetics with RealKcat.
Not available
S-EPMC11844551 | biostudies-literature
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