Sort   by:  
 Page size 
GenomicsContext Dependency of Set1/COMPASS Mediated H3 Lysine 4 Trimethylation
The stimulation of trimethylation of histone H3 lysine 4 (H3K4) by H2B monoubiquitination (H2Bub) has been widely studied with multiple mechanisms proposed for this form of histone crosstalk. Cps35/Swd2 within COMPASS is considered to bridge these processes. However, a truncated form of Set1 (762-Se...
ORGANISM(S): Saccharomyces cerevisiae 
2014-01-09 | E-GEOD-53241 | biostudies-arrayexpress
ProteomicsMass spectrometry-based characterization of SET1/COMPASS complex in Caenorhabditis elegans
Changes in histone post-translational modifications are associated with aging through poorly defined mechanisms. Histone 3 lysine 4 (H3K4) methylation at promoters is deposited by SET1 family methyltransferases acting within conserved multiprotein complexes known as COMPASS. Using co-immunopurificat...
ORGANISM(S): Caenorhabditis elegans 
2021-12-08 | PXD029904 | Pride
Caenorhabditis elegans Set1/compass complex Interactome Nanolc-ms/ms 
ProteomicsPhysical and functional interaction between SET1/COMPASS complex component CFP-1 and a Sin3S HDAC complex in C. elegans
The CFP1 CXXC zinc finger protein targets the SET1/COMPASS complex to nonmethylated CpG rich promoters to implement tri-methylation of histone H3 Lys4 (H3K4me3). Although H3K4me3 is widely associated with gene expression, the effects of CFP1 loss vary, suggesting additional chromatin factors contrib...
ORGANISM(S): Caenorhabditis elegans 
2019-09-27 | PXD015548 | Pride
Chromatin Set1/compass complex C. elegans Interactomics 
TranscriptomicsShg1p associated RNAs
RNA co-immunopurification with TAP-tagged Shg1p (a component of the Set1 histone methyltransferase complex, SET1C) from Saccharomyces cerevisiae. An untagged (BY4741) served as a control (Gerber et al. 2004). Cells were grown to mid-log phase in rich media and harvested by centrifugation. TAP-tagged...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-24 | E-GEOD-15247 | biostudies-arrayexpress
GenomicsTET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
TET proteins convert 5-methylcytosine to 5-hydroxymethylcytosine, an emerging dynamic epigenetic state of DNA that can influence transcription. Evidence has linked TET1 function to epigenetic repression complexes, yet mechanistic information, especially for the TET2 and TET3 proteins, remains limite...
ORGANISM(S): Mus musculus 
2013-02-07 | E-GEOD-36620 | biostudies-arrayexpress
GenomicsPhysical and functional interaction between the SET1/COMPASS complex component CFP-1/CXXC and a Sin3S HDAC complex
Physical and functional interaction between the SET1/COMPASS complex component CFP-1/CXXC and a Sin3S HDAC complex
PRJNA472359 | ENA
GenomicsN-terminal acetylation of the Set1-COMPASS fine-tunes H3K4 methylation patterns (ChIPseq for Set1 occupancy in ard1 deletion strain)
N-terminal acetylation of the Set1-COMPASS fine-tunes H3K4 methylation patterns (ChIPseq for Set1 occupancy in ard1 deletion strain)
PRJNA1065796 | ENA
UnknownPhysical and functional interaction between SET1/COMPASS complex component CFP-1 and a Sin3S HDAC complex in C. elegans.
Not available
S-EPMC6868398 | biostudies-literature
TranscriptomicsTranscription profiling by array of fission yeast mutants of the Set1/Compass complex under steady-state and dynamic conditions to analyze the role of histone 3 lysine 4 methylation in transcription
Genome-wide analysis of the role of Histone 3 lysine 4 methylation in S. cerevisiae transcription by analyzing different mutants of the Set1/Compass complex, under steady-state and dynamic conditions
ORGANISM(S): Saccharomyces cerevisiae 
2011-02-18 | E-TABM-486 | biostudies-arrayexpress
GenomicsTET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS
PRJNA153707 | ENA
Sort   by:  
 Page size