Sort   by:  
 Page size 
ProteomicsStructural, biochemical and functional characterization of the essential host factor SETD3 in complex with the enterovirus CV-B3 2A protease
Enteroviruses cause a number of medically relevant and widespread human diseases with no approved antiviral therapies currently available. We have previously identified the actin histidine methyltransferase SETD3 as critically important for enterovirus infection through a protein-protein interaction...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD024127 | Pride
Ap-ms Host-pathogen interactions Enterovirus Setd3 2a protease 
ProteomicsThe SETD3 interacting protein was identified and screened by TurboID method, and Search for potential histidine methylation modification sites
we employed a TurboID approach that utilized a modified promiscuous biotin ligase BirA for proximity labeling by fusing SETD3 with this enzyme, By introducing biotin, cellular fractions of SETD3-TurboID-transfected cells, both cytosolic and chromatin fractions, underwent immunoprecipitation, followe...
ORGANISM(S): Homo sapiens (Human) 
2024-04-16 | PXD050556 | Pride
Setd3 Methylation Hela s3 
ProteomicsThe SETD3 interacting protein was identified and screened by TurboID method, and Search for potential histidine methylation modification sites
we employed a TurboID approach that utilized a modified promiscuous biotin ligase BirA for proximity labeling by fusing SETD3 with this enzyme, By introducing biotin, cellular fractions of SETD3-TurboID-transfected cells, both cytosolic and chromatin fractions, underwent immunoprecipitation, followe...
ORGANISM(S): Homo sapiens (Human) 
2024-03-12 | PXD046472 | Pride
Turboid Hela s3 Lc-ms/ms 
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of control, SETD6 Knock-out, SETD3 knock-out and SETD6+SETD3 knock-out HeLa cells Transcriptomes
Next Generation Sequencing Facilitates Quantitative Analysis of control, SETD6 Knock-out, SETD3 knock-out and SETD6+SETD3 knock-out HeLa cells Transcriptomes
PRJNA819059 | ENA
UnknownThe EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction.
Not available
S-EPMC11099015 | biostudies-literature
GenomicsSETD3 actin histidine methyltransferase regulates intestinal epithelial barrier integrity and mucosal inflammation
SETD3 actin histidine methyltransferase regulates intestinal epithelial barrier integrity and mucosal inflammation
PRJNA1516061 | ENA
UnknownChromatin associated SETD3 negatively regulates VEGF expression.
Not available
S-EPMC5109252 | biostudies-literature
GenomicsSETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM
SETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM
PRJNA1020753 | ENA
OtherSETD3-mediated histidine methylation of MCM7 regulates DNA replication by facilitating chromatin loading of MCM
The minichromosome maintenance complex (MCM) DNA helicase is an important replicative factor during DNA replication. The proper chromatin loading of MCM is a key step to ensure replication initiation during G1/S phase. Because replication initiation is regulated by multiple biological cues, addition...
ORGANISM(S): Homo sapiens 
2024-03-12 | GSE243937 | GEO
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of control, SETD6 Knock-out, SETD3 knock-out and SETD6+SETD3 knock-out HeLa cells Transcriptomes
The goal of this study was to identifiy shared target genes for SETD3 and SETD6.
ORGANISM(S): Homo sapiens 
2023-03-01 | GSE199250 | GEO
Sort   by:  
 Page size