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MetabolomicsUntangling the wine metabolome by combining untargeted SMPE-GCxGC-TOF-MS and sensory analysis to profile Sauvignon blanc co-fermented with seven different yeasts
Saccharomyces cerevisiae (SC) is the main driver of alcoholic fermentation however for aroma and flavour formation in wine non-Saccharomyces species can have a powerful effect. This study aimed to compare untargeted volatile compound profiles from SPME-GCxGC-TOF-MS and sensory analysis data of Sauvi...
2015-08-19 | MTBLS212 | MetaboLights
TranscriptomicsLiver expression data from four mouse strains treated with vehicle or PF-04287881 for seven days
PF-04287881 induced varying degrees of liver necrosis and phospholipidosis in a 34-inbred strain Mouse Diversity Panel (MDP) study. Four strains with differing susceptibilities to these phenotypes (MA/MyJ, NZW/LacJ, SM/J, WSB/EiJ) were selected for analysis of gene expression changes in the liver. T...
ORGANISM(S): Mus musculus 
2016-10-21 | E-GEOD-52620 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse strains (10) across 7 brain regions
Survey of gene expression in ten common inbred strains of laboratory mouse. Seven brain regions examined: amygdala, basal ganglia, cerebellum, frontal cortex, hippocampus, cingulate cortex, olfactory bulb. Experiment Overall Design: Tissue from three animals was pooled on each array. Three biolog...
ORGANISM(S): Mus musculus 
2008-06-13 | E-GEOD-5055 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of fungus Penicillium oxalicum and its laeA deletion strains in 24h and 60h
The goals of this study are to compare differential gene expressions for Penicillium oxalicum wild type strain (WT), and laeA knockout strain (ΔlaeA) in different development phase. The deletion of laeA downregulated genes involved in oxidation- reduction process, alkaloid metabolic process, and tra...
ORGANISM(S): Penicillium oxalicum 
2015-07-27 | E-GEOD-71287 | biostudies-arrayexpress
GenomicsTE-associated chromatin variation in mice livers
Chromatin accessibility is a hallmark of active regulatory function in the genome and variation of chromatin accessibility across individuals has been shown to contribute to complex traits and disease susceptibility. However, the mechanisms responsible for chromatin variation among different individ...
ORGANISM(S): Mus musculus 
2016-07-14 | E-GEOD-75770 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of the Hippocampus from Six Inbred Strains of Mice Suggests Basis for Sex-Specific Susceptibility and Severity of Neurological Disorders
Identifying sex differences in gene expression within the brain is critical for determining why multiple neurological and behavioural disorders differentially affect males and females. Several are more common or severe in males (e.g., autism and schizophrenia) or females (e.g., Alzheimer’s disease...
ORGANISM(S): Mus musculus 
2016-01-06 | E-GEOD-76567 | biostudies-arrayexpress
Genomics
Seven Flavobacterium strains
PRJNA953854 | ENA
TranscriptomicsComparative genomic hybridization of twenty four Salmonella enteritidis strains from six phage types
In this study differences at the genetic level of 24 S. Enteritidis strains from six phage types were compared using Comparative Genomic Hybridisation (CGH) DNA microarrays to determine why some certain phage types are 'less successful' in causing human infection.
ORGANISM(S): Salmonella typhimurium 
2008-08-02 | E-MEXP-1720 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of strains of Paxillus involutus that show different abilities in formation of ectomycorrhizal associations with birch (Betula pendula)
A microarray analysis was conducted to investigate transcriptional differences between strains of Paxillus involutus that show different abilities in formation of ectomycorrhizal associations with birch (Betula pendula). Our goal was to identify genes that showed differential regulation from compari...
ORGANISM(S): Ectomycorrhizal tissue: Paxillus involutus/Betula pendula 
2004-10-05 | E-MEXP-179 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of different regions of mouse brain to study adult mouse gene expression patterns in common strains.
Adult mouse gene expression patterns in common strains. Experiment Overall Design: six mouse strains and seven brain regions were analyzed
ORGANISM(S): Mus musculus 
2007-09-14 | E-GEOD-3327 | biostudies-arrayexpress
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