Sex modification

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Unknown (1432)
Transcriptomics (265)
Proteomics (243)
Genomics (195)
Methylation profiling (12)
Metabolomics (6)
Genomic (4)
Other (4)
Models (3)

Organisms

Homo sapiens (101)
Mus musculus (94)
Drosophila melanogaster (45)
Caenorhabditis elegans (33)
Rattus norvegicus (13)
Gallus gallus (5)
Bos taurus (5)
Macaca mulatta (3)
Pan troglodytes (3)
Danio rerio (3)
Pimephales promelas (2)
Streptomyces coelicolor A3(2) (2)
Plasmodium falciparum 3D7 (2)
Canis lupus familiaris (2)
Sus scrofa (2)
Rattus (1)
Beauveria bassiana (1)
Ptomaphagus hirtus (1)
Schizophyllum commune (1)
Caenorhabditis briggsae (1)
Rattus sp. (1)
Medicago sativa (1)
Aspergillus fumigatus (1)
Schistosoma mansoni (1)
Medicago truncatula (1)
Apis mellifera (1)
Salmo salar (1)
Oncorhynchus mykiss (1)
Plasmodium falciparum (1)
Pseudomonas aeruginosa (1)

Organisms

Mus musculus (49)
Drosophila melanogaster (22)
Homo sapiens (15)
Chlamydomonas reinhardtii (4)
Rattus norvegicus (4)
Caenorhabditis elegans (3)
Spodoptera frugiperda (2)
Coccinia grandis (1)
Silene (1)
Diospyros lotus (1)
Bostrychia moritziana (1)
Drosophila miranda (1)
Anopheles sinensis (1)
Bos grunniens (1)
Artemia franciscana (1)
Ruditapes philippinarum (1)
Monopterus albus (1)
Daphnia pulex (1)
Ovis aries (1)
Oryzias latipes (1)
Danio rerio (1)
Arabidopsis thaliana (1)
Bos taurus (1)
Gallus gallus (1)
unidentified (1)

Repository

biostudies-arrayexpress (256)
pride (218)
ENA (136)
geo (84)
MassIVE (21)
MetaboLights (6)
dbGaP (4)
BioModels (3)
jPOST (3)
EGA (1)

Tissue

Brain (31)
Blood plasma (20)
Heart (12)
Blood (8)
Blood cell (7)
Kidney (7)
Liver (7)
Tooth enamel (7)
Accessory sex gland (6)
Blood serum (6)
Cell culture (6)
Testis (6)
Urine (6)
Ovary (5)
Retina (5)
Spermatozoon (5)
Whole body (5)
Embryonic stem cell (4)
Retinal cell (4)
Saliva (4)
Blood platelet (3)
Microglial cell (3)
Pheromone gland (3)
Primary cell (3)
White adipose tissue (3)
Bone (2)
Bone marrow (2)
Brown adipose tissue (2)
Cerebrospinal fluid (2)
Ejaculatory duct (2)

Disease

Alzheimer's disease (7)
Cardiovascular system disease (5)
Retinal degeneration (4)
Atherosclerosis (3)
Type 2 diabetes mellitus (3)
Amyotrophic lateral sclerosis (2)
Aortic valve stenosis (2)
Disease free (2)
Obesity (2)
Osteoarthritis (2)
Plasmodium falciparum malaria (2)
Schizophrenia (2)
Type 1 diabetes mellitus (2)
Microscopic Polyangiitis (1)
Fetal growth restriction (1)
Rett syndrome (1)
Sham infected (1)
Papillary Carcinoma (1)
Spinal muscular atrophy (1)
Aniridia (1)
Bacterial vaginosis (1)
Brain cancer (1)
Brain glioblastoma multiforme (1)
Brain glioma (1)
COVID-19 (1)
Cardiomyopathy (1)
Cerebrovascular disease (1)
Chronic fatigue syndrome (1)
Diabetic angiopathy (1)
Duchenne muscular dystrophy (1)

Technology Type

Mass Spectrometry (218)
Shotgun proteomics (110)
Bottom-up proteomics (62)
Data-dependent acquisition (39)
Data-independent acquisition (15)
Affinity purification coupled with mass spectrometry proteomics (11)
Gel-based experiment (9)
SWATH MS (6)
HDMSE (5)
SRM/MRM (5)
Mass spectrometry (4)
Top-down proteomics (3)
All-ion fragmentation (2)
DiaPASEF (2)
NMR spectroscopy assay (1)
Mass spectrometry assay (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
MSE (1)

Instrument Platform

Q Exactive (6)
Illumina HiSeq 2500 (5)
LTQ Orbitrap Elite (3)
Orbitrap Fusion (3)
Illumina NovaSeq 6000 (2)
NextSeq 500 (2)
LTQ Orbitrap (2)
Orbitrap Fusion Lumos (2)
Q Exactive Plus (2)
Liquid Chromatography MS - negative - reverse phase (2)
PromethION (1)
Sony SH800 (1)
The TLDA cards were analyzed on the Applied Biosystems 7900HT Real-Time PCR System. (1)
Illumina Genome Analyzer (1)
Axon- GenePix4000B (1)
Illumina Genome Analyzer II (1)
- (1)
Illumina HiSeq 1500 (1)
NextSeq 550 (1)
6550 iFunnel Q-TOF LC/MS (1)
In-house built IMS-MS with Agilent TOF MS (1)
LTQ (1)
LTQ FT (1)
LTQ Orbitrap Velos (1)
Orbitrap Eclipse (1)
Q Exactive HF-X (1)
TimsTOF Pro (1)
Flow injection analysis MS – alternating (1)
Matrix-assisted laser desorption-ionisation imaging MS - (1)
Nuclear Magnetic Resonance (NMR) - (1)

Publication Date

2024 (56)
2011 (52)
2025 (49)
2026 (46)
2010 (44)
2023 (37)
2014 (37)
2022 (31)
2012 (30)
2021 (28)
2016 (27)
2013 (27)
2019 (20)
2015 (19)
2017 (18)
2020 (15)
2009 (13)
2008 (13)
2018 (10)
2007 (8)
2005 (5)
2006 (2)
2004 (1)
2002 (1)

CHEBI ID

CHEBI:187409 (1)
CHEBI:132586 (1)
CHEBI:197376 (1)
CHEBI:197375 (1)
CHEBI:183805 (1)
CHEBI:229268 (1)
CHEBI:62346 (1)
CHEBI:37655 (1)
CHEBI:37714 (1)
CHEBI:18040 (1)
CHEBI:196466 (1)
CHEBI:140999 (1)
CHEBI:15670 (1)
CHEBI:156040 (1)
CHEBI:156044 (1)
CHEBI:136265 (1)
CHEBI:149571 (1)
CHEBI:66973 (1)
CHEBI:136132 (1)
CHEBI:132590 (1)
CHEBI:132589 (1)
CHEBI:140365 (1)
CHEBI:53455 (1)
CHEBI:65136 (1)
CHEBI:183798 (1)
CHEBI:183799 (1)
CHEBI:183800 (1)
CHEBI:137552 (1)
CHEBI:134243 (1)
CHEBI:86369 (1)

Metabolite Name

Linoelaidic acid (2)
2-Methyl-4-pentenoic acid (2)
Pelargonic acid (2)
Hydroxypropionic acid (2)
Indoleacetic acid (2)
Ketoleucine (2)
Rhamnose (2)
Myristoleic acid (2)
Citrulline (2)
Shikimic acid (2)
Palmitoleic acid (2)
Phenylpyruvic acid (2)
Adrenic acid (2)
Pimelic acid (2)
Malonic acid (2)
Gluconolactone (2)
Baseline (1)
Standard mixture (1)
Nonadeca-10Z-enoic acid (1)
6-Octadecylenic acid (1)
Bishomo-gamma-linolenic acid (1)
N-Acetyl-alpha-neuraminic acid (1)
3-Aminobenzoic acid (1)
5-Amino-levulinic acid (1)
TG(62:9) (1)
TG(62:8) (1)
TG(60:13) (1)
TG(60:8) (1)
TG(60:6) (1)
TG(58:12) (1)

IsPrivate

False (3)

First Public Date

2014 (27)
2025 (21)
2024 (19)
2026 (12)
2023 (11)
2022 (9)
2021 (9)
2017 (8)
2020 (4)
2013 (4)
2019 (3)
2018 (3)
2016 (3)
2015 (3)

Modelling Approach

Ordinary differential equation model (3)

Modification

4x(2)H labeled dimethylated residue (1)

Study type

Transcription profiling by array (119)
ChIP-seq (35)
ChIP-chip by tiling array (22)
RNA-seq of coding RNA (18)
Comparative genomic hybridization by array (10)
Methylation profiling by array (9)
Unknown experiment type (7)
Transcription profiling by RT-PCR (7)
Methylation profiling by high throughput sequencing (4)
ChIP-chip by array (3)
Other (3)
Human - High-throughput sequencing (2)
Bisulfite-seq (2)
MicroRNA profiling by array (2)
RNA-seq of non coding RNA (2)
Transcription profiling by SAGE (1)
Animal - Single-cell sequencing (1)
Human - One-color microarray (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Trajectory (1)
Transcription profiling by tiling array (1)
ATAC-seq (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of total RNA (1)

Release Date

2025 (187)
2023 (175)
2022 (175)
2021 (153)
2024 (152)
2020 (120)
2019 (95)
2018 (85)
2017 (78)
2014 (67)
2011 (62)
2010 (61)
2016 (59)
2015 (57)
2012 (50)
2013 (43)
2026 (22)
2009 (13)
2008 (13)
2007 (9)
2006 (5)
2005 (3)
2004 (1)
2002 (1)
2001 (1)
1998 (1)

Lab affiliation

Center for Reproductive Evolution, Biology Department, Syracuse University (3)
Center for Translational Vision Research, Department of Ophthalmology, Gavin Herbert Eye Institute, University of California, Irvine, Irvine, CA, 92697, USA; Department of Physiology and Biophysics, Department of Chemistry, Department of Molecular Biology and Biochemistry; University of California, Irvine, Irvine, CA, 92697, USA (3)
Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461, United States (3)
IRCCS Istituto G Gaslini (3)
Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 (2)
Department of Life and Environmental Sciences, University of Cagliari (2)
Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden (2)
Dr. Elke Hammer Universitätsmedizin Greifswald Interfakultäres Institut für Genetik und Funktionelle Genomforschung Abteilung für Funktionelle Genomforschung Felix-Hausdorff-Straße 8 17487 Greifswald Germany (2)
Institute of Bioinformatics, Bangalore - 560066, India (2)
MIVEGEC, Université de Montpellier, IRD, CNRS, Montpellier, France. (2)
Professor of biochemistry, deputy head of department Biomarker Research Group - group leader Department of Biochemistry and Molecular Biology Faculty of Medicine University of Debrecen 4032 Debrecen, Egyetem ter 1. (2)
Shanghai Hoogen Biotechnology Co., Ltd. (2)
Tumor Biology Moffitt Cancer Center Tampa, FL, USA (2)
1 Department of Cancer Biology, Dana–Farber Cancer Institute, Boston, MA, USA. 2 Department of Cell Biology, Harvard Medical School, Boston, MA, USA. (1)
1 Department of Medicine - Western Health, The University of Melbourne, Melbourne, Australia The Australian Institute for Musculoskeletal Science (AIMSS), Western Health, Victoria University and The University of Melbourne, Melbourne, Australia 3 Institute for Health and Sport, Victoria University, Melbourne, Australia (1)
1. Laboratório de Neurofisiologia, Departamento de Ciências Fisiológicas, Instituto de Biologia Roberto Alcantara Gomes, Universidade do Estado do Rio de Janeiro (UERJ), Av. Prof. Manuel de Abreu 444, 5 andar – Vila Isabel, Rio de Janeiro, RJ, 20550-170, Brazil. (1)
1Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
1Gavin Herbert Eye Institute –Brunson Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, University of California Irvine, Irvine, CA 92697, USA 2Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA 3Department of Chemistry, University of California Irvine, Irvine, CA 92697, USA 4Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, USA (1)
Ackermannweg 4, 55128 Mainz, Germany (1)
Anesthesiology Department, The First Affiliated Hospital of Ningbo University, Ningbo, China (1)
Associate Professor & Co-Chair, Biology Division Indian Institute of Science Education and Research (IISER Pune) Dr. Homi Bhabha Road, Pashan, Pune-411008. Maharashtra, India. (1)
Baylor College of Medicine (1)
BioArch South, Waitati, New Zealand (1)
Biomarker Research Group - group leader Department of Biochemistry and Molecular Biology Faculty of Medicine University of Debrecen Hungary (1)
Boston University, School of Medicine (1)
Brigham and Women's Hospital, Harvard Medical School (1)
CDSS Bioanalytical Facility, Pharmacology & Therapeutics, LIV-SRF, University of Liverpool, UK (1)
CSIR-Indian Institute of chemical Technology (1)
Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, Louisiana, 70112, USA (1)
Carnegie Mellon University (1)

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Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

We report the identification of 67 previously undescribed histone modifications, increasing the current number of known histone marks by about 70%. We further investigated one of the marks, lysine crotonylation (Kcr), confirming that it represents an evolutionarily-conserved histone posttranslationa...

ORGANISM(S): Mus musculus

2011-10-06 | E-GEOD-32663 | biostudies-arrayexpress

Drosophila Sex Hierarchy Regulated Gene Expression in 48 hour APF Pupae

Drosophila melanogaster undergoes a complete metamorphosis, during which time the larval male and female forms transition into sexually dimorphic, reproductive adult forms. To understand this complex morphogenetic process at a molecular-genetic level, we performed whole genome microarray analyses. ...

ORGANISM(S): Drosophila melanogaster

2009-02-10 | E-GEOD-11311 | biostudies-arrayexpress

SILAC-Based Proteomics of Primary Human Kidney Cells treated with Sex Hormones.

Male sex predispose to many kidney diseases. Considering that androgens exert deleterious effects in a variety of cell types within kidney, we hypothesized that dihydrotestosterone (DHT) would impair the biology of the renal tubular cell by inducing changes in the proteome. We employed stable isotop...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2017-03-31 | MSV000080854 | MassIVE

Cross-sectional association of salivary proteins with age, sex, body mass index, smoking, and education

In a cross-sectional approach, we analyzed the influence of age, sex, body mass index (BMI), smoking, and education on salivary protein signatures in whole saliva samples of 187 individuals. Subjects were randomly selected from the population-based Study of Health in Pomerania (SHIP-Trend).

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2019-03-13 | MSV000083569 | MassIVE

Sexual dimorphism in mammals is mostly attributable to sex-related hormonal differences in fetal and adult tissues; however, this may not be the sole determinant. Though genetically-identical for autosomal chromosomes, male and female preimplantation embryos could display sex-specific transcriptiona...

ORGANISM(S): Bos taurus

2010-03-09 | E-GEOD-17921 | biostudies-arrayexpress

Label free SWATH proteomics reveals sex-biased proteins potentially associated with sex expression and modification in dioecious C. grandis

Dioecy is an important sexual system wherein, male and female flowers are borne on separate unisexual plants. Knowledge of sex-related differences can enhance our understanding in molecular and developmental processes leading to unisexual flower development. Coccinia grandis is a dioecious species b...

ORGANISM(S): Coccinia grandis

2019-07-29 | PXD011064 | Pride

Sex-different hepatic glycogen content, glucose and amino acid output in rats.

In the present study we tested the hypothesis that male and female rat livers respond differently to a change in nutrient availability or to insulin treatment. We compared hepatic gene expression, hepatic glycogen and glucose output, insulin sensitivity and amino acids, using healthy rats. Keywords...

ORGANISM(S): Rattus norvegicus

2011-03-01 | E-GEOD-20601 | biostudies-arrayexpress

The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner

This SuperSeries is composed of the following subset Series: GSE39472: X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner [ChIP-Seq data] GSE39473: The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agil...

ORGANISM(S): Mus musculus

2012-07-31 | E-GEOD-39222 | biostudies-arrayexpress

Transcription profiling of chicken 18 day embryonic chicken heart, brain, and gonad to determine sex specific gene expression

The contrasting dose of sex chromosomes in males and females potentially introduces a large-scale imbalance in levels of gene expression between sexes. In many organisms dosage compensation has thus evolved to equalize sex-linked gene expression in males and females1,2, in mammals achieved by X chro...

ORGANISM(S): Gallus gallus

2008-11-06 | E-GEOD-8693 | biostudies-arrayexpress

The X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex specific manner [Agilent array data]

Embryogenesis requires the timely and coordinated activation of developmental regulators. It has been suggested that the recently discovered class of histone demethylases (UTX and JMJD3) that specifically target the repressive H3K27me3 modification play an important role in the activation of M-bM-^...

ORGANISM(S): Mus musculus

2012-07-31 | E-GEOD-39473 | biostudies-arrayexpress

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2164 Results

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