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ProteomicsSerum Proteomics of Severe Fever with Thrombocytopenia Syndrome Patients
Dabie bandavirus, also termed as severe fever with thrombocytopenia syndrome virus (SFTSV), was first isolated in China in 2010. At this time, the virus was found to have spread to South Korea, Japan, and other countries. A high case fatality rate is reported for SFTS, ranging from 12–50% within var...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD033989 | Pride
Sfts Serum proteomics Sftsv Lc-ms/ms 
GenomicsTranscriptomic analysis of blood samples collected from SFTS patients
Transcriptomic analysis of blood samples collected from SFTS patients
PRJNA603492 | ENA
GenomicsSingle-cell landscape of peripheral immune responses to fatal SFTS
Single-cell landscape of peripheral immune responses to fatal SFTS
PRJNA732640 | ENA
GenomicsAnalysis of SFTS pathogenesis based on single-cell RNA sequencing of monocytes
Analysis of SFTS pathogenesis based on single-cell RNA sequencing of monocytes
PRJNA1214776 | ENA
GenomicsMolecular signatures of inflammatory profile and B-cell function in SFTS patients
Molecular signatures of inflammatory profile and B-cell function in SFTS patients
PRJNA627941 | ENA
TranscriptomicsSingle-cell landscape of peripheral immune responses to fatal SFTS
We performed scRNA-seq on 27 PBMC samples from 15 SFTS patients (including four deceased and 11 surviving) and four healthy controls. We found that the immune cell landscape was reprogrammed in SFTS and characterized by monocyte shift to intermediate type along with complement activation, perturbati...
ORGANISM(S): Homo sapiens 
2021-08-14 | GSE175499 | GEO
TranscriptomicsAnalysis of SFTS pathogenesis based on single-cell RNA sequencing of monocytes
Severe fever with thrombocytopenia syndrome (SFTS) is a newly identified tick-borne viral disease with a high mortality rate. Monocytes are known to play an important role in the pathogenesis of SFTS, but the distinct subpopulations of monocytes associated with the disease progression and their role...
ORGANISM(S): Homo sapiens 
2025-01-27 | GSE287827 | GEO
TranscriptomicsMolecular signatures of inflammatory profile and B-cell function in SFTS patients
Severe fever with thrombocytopenia syndrome banyangvirus (SFTSV) induces immunopathogenic disease with high fatality rate. Despite serious health concern, the mechanisms underlying clinical manifestations are largely unknown. Here, we applied targeted proteomics and single-cell transcriptomics analy...
ORGANISM(S): Homo sapiens 
2020-10-01 | GSE149313 | GEO
TranscriptomicsTranscriptomic analysis of blood samples collected from SFTS patients
To investigate the mechanisms that contribute to the pathogenesis resulting from SFTSV infection, transcriptomic analysis was performed with blood samples collected from SFTS patients.
ORGANISM(S): Homo sapiens 
2020-01-29 | GSE144358 | GEO
UnknownNeutralizing mAbs against SFTS Virus Gn Protein Show Strong Therapeutic Effects in an SFTS Animal Model.
Not available
S-EPMC9416629 | biostudies-literature
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