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TranscriptomicsTranscription profiling of S. cerevisiae sgs1 mutant and wild type strains grown under DNA damaging and control conditions
Wild type and sgs1 null yeast were grown under DNA damaging (with MMS) conditions or without treatment to log phase and their transcriptional profiles compared. The human aging diseases Werner and Bloom syndromes are a result of mutation of the WRN and BLM genes, respectively. The SGS1 gene of Sacch...
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-07 | E-GEOD-423 | biostudies-arrayexpress
GenomicsThe genome of Plasmodium relictum SGS1
The genome of Plasmodium relictum SGS1
PRJEB9074 | ENA
GenomicsPlasmodium relictum strain:SGS1
Plasmodium relictum strain:SGS1 Transcriptome or Gene expression
PRJNA196990 | ENA
TranscriptomicsSGS1 synthetic lethality
Assessment of synthetic lethality between an sgs1 null mutation and Yeast Deletion mutations Keywords = SGS1 Keywords = yeast Keywords = deletion Keywords = synthetic lethality Keywords = tag Keywords = barcode Keywords: repeat sample
ORGANISM(S): Saccharomyces cerevisiae 
2004-11-05 | GSE1757 | GEO
ProteomicsPhosphoproteomic Datasets for Mec1/ATR Signaling Upon Hyper-Resection (TMT Supplement)
The Mec1/ATR kinase is crucial for genome maintenance, although the mechanisms by which it controls DNA repair pathways remain elusive. Here we uncovered a role for Mec1/ATR in controlling homologous recombination (HR) factors in response to hyper-resection of DNA ends. Cells lacking RAD9, a checkpo...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-03-10 | PXD023438 | Pride
Mec1 Sgs1 Silac Phosphoproteomics Resection 
TranscriptomicsThe expression profiles of WT and sgs1△ after tangeretin treatment
Tangeretin is a member of the polymethoxyflavones in citrus peel, which have been of interest due to their anti-atherogenic, anti-inflammatory, and anti-carcinogenic properties. However, their detailed target pathways have not been fully discovered. We applied the notion of chemical-genetic and gene...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-29 | GSE43799 | GEO
TranscriptomicsChIP-on-chip of Sgs1 and gammaH2A and DNA:RNA hybrids in wild type and SGS1 mutants
Sgs1 is a DNA helicase with roles in DNA replication and repair. DNA repair proteins have been linked to genome instability in part by altering the landscape of DNA:RNA hybrids. Here, we mapped the Sgs1 binding profile along with the profile of DNA:RNA hybrids and gammaH2A genome-wide in an effort t...
ORGANISM(S): Saccharomyces cerevisiae 
2018-01-30 | E-MTAB-5582 | biostudies-arrayexpress
TranscriptomicsThe expression profiles of WT and sgs1△ after tangeretin treatment
Tangeretin is a member of the polymethoxyflavones in citrus peel, which have been of interest due to their anti-atherogenic, anti-inflammatory, and anti-carcinogenic properties. However, their detailed target pathways have not been fully discovered. We applied the notion of chemical-genetic and gene...
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-29 | E-GEOD-43799 | biostudies-arrayexpress
GenomicsSaccharomyces cerevisiae
SGS1 synthetic lethality
PRJNA90511 | ENA
UnknownRegulatory control of Sgs1 and Dna2 during eukaryotic DNA end resection.
Not available
S-EPMC6442620 | biostudies-literature
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