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UnknownRNA-DNA hybrids promote the expansion of Friedreich's ataxia (GAA)n repeats via break-induced replication.
Not available
S-EPMC5909440 | biostudies-literature
UnknownFinal 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naive Chronic Myeloid Leukemia Patients Trial.
Not available
S-EPMC5118045 | biostudies-literature
TranscriptomicsGene expression changes associated with progression and response in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is a hematopoetic stem cell disease with distinct biological and clinical features. The biological foundation of the stereotypical progression from chronic phase through accelerated phase to blast crisis is poorly understood. We used DNA microarrays to compare gene exp...
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-4170 | biostudies-arrayexpress
UnknownNovel insights into breast cancer copy number genetic heterogeneity revealed by single-cell genome sequencing.
Not available
S-EPMC7220379 | biostudies-literature
TranscriptomicsGlobal gene expression changes in patient-derived CML cell line K562 after short- and long-term BCR-ABL kinase inhibition.
K562 cells were treated with the BCR-ABL kinase inhibitor dasatinib over an extended period of time to determine how BCR-ABL inhibition affects BCR-ABL-dependent negative feedback and erythropoietin receptor (EPO-R) signaling. Specifically, what types of changes (upregulation versus downregulation)...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-51083 | biostudies-arrayexpress
UnknownDuration of anticoagulation for venous thromboembolism in pediatric patients: Evaluation of the Duration of Therapy for Thrombosis in Children (Kids-DOTT) trial outcomes at 2 years.
Not available
S-EPMC11786982 | biostudies-literature
TranscriptomicsRNA-seq analysis following REVERBalpha knockdown in fibroblasts
The aim of the study was to identify how REVERBalpha modulates myofibroblast differentiation; by sequencing fibroblasts twelve and twenty-four hours after siRNA knockdown.
ORGANISM(S): Mus musculus 
2019-12-10 | E-MTAB-8499 | biostudies-arrayexpress
UnknownResults of the ICTuS 2 Trial (Intravascular Cooling in the Treatment of Stroke 2).
Not available
S-EPMC5134910 | biostudies-literature
UnknownAcceleration of the loss of the first-phase insulin response during the progression to type 1 diabetes in diabetes prevention trial-type 1 participants.
Not available
S-EPMC3837047 | biostudies-literature
UnknownA trial of imaging selection and endovascular treatment for ischemic stroke.
Not available
S-EPMC3690785 | biostudies-literature
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