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TranscriptomicsDNA Methylation Profiling Defines Clinically Relevant Biological Subsets of Non-small Cell Lung Cancer
PURPOSE: Non-small cell lung cancers (NSCLC) comprise multiple distinct biological groups with different prognoses. For example, patients with epithelial-like (EL) tumors have a better prognosis and exhibit greater sensitivity to inhibitors of the epidermal growth factor receptor (EGFR) pathway than...
ORGANISM(S): Homo sapiens 
2012-03-03 | E-GEOD-36216 | biostudies-arrayexpress
TranscriptomicsAgilent 244A aCGH array for comparison of lung tumor CNA to high-throughput sequencing data
1 lung tumor was profiled for copy-number alterations with the high-resolution Agilent 244A aCGH Array. One lung tumor sample were assayed on the Agilent Human Genome CGH 244A Microarrays with the intent of comparing the genomic alterations reported by the array platform with those reported by high-...
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20574 | biostudies-arrayexpress
TranscriptomicsAssessment of mutation on expression levels
One lung tumor and its adjacent normal were profiled for expression levels with the Affymetrix HGU133 plus 2.0 array. One lung tumor sample and its adjacent normal were assayed on the Affymetrix HG-U133 plus 2.0 array to assess the effects of mutation on expression.
ORGANISM(S): Homo sapiens 
2011-02-21 | E-GEOD-20578 | biostudies-arrayexpress
GenomicsThe mutation spectrum revealed by paired genome sequences from a lung cancer patient

Whole genome sequencing was applied to tumor and adjacent normal lung tissue in an individual non-small-cell lung cancer patient. We present an analysis of somatic changes identified throughout the tumor genome, including single-nucleotide variants, copy number variants, and large-scale chrom...

phs000299.v1.p1 | EGA
UnknownNeoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial.
Not available
S-EPMC9556329 | biostudies-literature
TranscriptomicsEffect of unilateral naris occlusion on gene profile in mouse olfactory mucosa.
Unilateral naris occlusion was performed the day after birth in three FVB strain mice. At 25 days of age olfactory mucosa was collected from open nasal fossa, the occluded nasal fossa and from three untreated mice. Total RNA was extracted and gene profiles among these three treatment conditions were...
ORGANISM(S): Mus musculus 
2012-08-22 | E-GEOD-33833 | biostudies-arrayexpress
Genomicsena-DATASET-Genentech-22-08-2012-06:56:27:875-9 - samples
Whole genome sequencing of SCLC tumor/normal samples
EGAD00001000221 | EGA
GenomicsLung normal control - samples
SCLC matched normal genotypes
EGAD00010000278 | EGA
GenomicsSmall Cell Lung Carcinoma - samples
SCLC tumor genotypes
EGAD00010000276 | EGA
Genomicsena-DATASET-Genentech-22-08-2012-07:03:30:871-10 - samples
Exome capture sequencing of SCLC tumor/normal pairs and cell lines
EGAD00001000222 | EGA
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