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Using ChIP-DSL technology from Aviva Systems Biology to find out the whole genome targets for ZIP transcription repressor We analyzed arrays using specific ZIP antibody and negative control to acquire the enriched ratio of each gene
ORGANISM(S): Homo sapiens 
The molecular explanation for tamoxifen serving as a breast cancer treatment but displaying partial estrogenic in the uterus is not known. Previously, we reported that differential promoter context and cofactor recruitment contribute to the tissue specificity of tamoxifen. Here, we investigated the ...
ORGANISM(S): Homo sapiens 
Using ChIP-DSL technology from AVIVA SYSTEMS BIOLOGY to find out the whole genome targets for LSD1, MTA1, MTA2, and MTA3 We analyzed arrays using antibodies against LSD1, MTA1, MTA2, or MTA3 and negative control to acquire the enriched ratio of each gene.
ORGANISM(S): Homo sapiens 
Low back pain (LBP) is one of the most prevalent conditions which need medical advice and result in chronic disabilities. Degenerative disc disease (DDD) is a common reason for LBP. A lot of researchers think that CEP degeneration play critical roles in the initiation and development of DDD. In rece...
ORGANISM(S): Homo sapiens 
We report that the winged helix transcription factor FOXA1 is unexpectedly associated with components of single and double stranded-DNA repair complexes. Biochemical studies and high-throughput approaches validated the hierarchical composition of this FOXA1-nucleated machinery and revealed the depen...
ORGANISM(S): Homo sapiens (Human) 
2016-06-08 | PXD004271 | Pride
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