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TranscriptomicsGene based expression changes in glioblastoma cells after downregulation of MPS1 kinase
Gene expression changes were analyzed in U251 GBM cells after downregulation of MPS1 by RNA interference technology at different time points Microarray analysis was used to compare the mRNA expression profile of siMPS1 silenced U251 cells compared to siNegative (siNeg) and untransfected (Control) ce...
ORGANISM(S): Homo sapiens 
2015-06-15 | E-GEOD-57091 | biostudies-arrayexpress
ProteomicsReverse phase protein arrays (RPPAs): effects of MPS1 inhibition on signaling pathways in GBM cells
To determine the biological effects of MPS1 inhibition (both by siRNA and Drug (NMSP715)) on signaling pathways in GBM cells (U251 &U87), we profiled the modulation of phosphorylated and non-phosphorylated proteins using RPPA Relative protein levels for each sample were determined by interpolation o...
ORGANISM(S): Homo sapiens 
2015-06-25 | E-GEOD-67502 | biostudies-arrayexpress
TranscriptomicsSenescence gene signature of radiation fibrosis
Radiation lung injury is characterized by early inflammation and late fibrosis. The causes underlying the chronic, progressive nature of radiation injury are poorly understood. Here, we report that the gene expression of irradiated lung tissue correlates with that observed in the lungs in aged anim...
ORGANISM(S): Mus musculus 
2013-11-01 | E-GEOD-41789 | biostudies-arrayexpress
TranscriptomicsExpression data from pheochromocytoma (PHEO) and paraganglioma (PGL) tumor samples
Genotype specific differences in expression profiles have been evaluated using human HuGene1.0-ST Gene Chips. In this dataset we include expression data obtained from 8 normal adrenal medulla and 45 PHEOs/PGLs patient samples. Viable appearing tissue from the center of the lesions was collected and ...
ORGANISM(S): Homo sapiens 
2013-11-12 | E-GEOD-39716 | biostudies-arrayexpress
UnknownSL-BioDP: Multi-Cancer Interactive Tool for Prediction of Synthetic Lethality and Response to Cancer Treatment.
Not available
S-EPMC6895978 | biostudies-literature
UnknownGlioma-BioDP: database for visualization of molecular profiles to improve prognosis of brain cancer.
Not available
S-EPMC10350252 | biostudies-literature
UnknownComputational analysis of the mesenchymal signature landscape in gliomas.
Not available
S-EPMC5345226 | biostudies-literature
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