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TranscriptomicsMicroarray Profile of Measles Virus Nucleocapsid Protein (MVNP) Regulated Gene Expression in RANKL and M-CSF stimulated normal human bone marrow derived non-adherent cells.
Paget’s disease of bone (PDB) is a chronic focal skeletal disorder that affects 2-3% of the population over the age of 60. PDB is inherited as an autosomal dominant trait with genetic heterogeneity. SQSTM1/p62 UBA domain mutation (p62P392L) is widely identified in PDB and has been shown to increase...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-29106 | biostudies-arrayexpress
TranscriptomicsMicroarray profile of p62P392L-regulated gene expression in RANKL and M-CSF stimulated normal human bone marrow derived non-adherent cells
Paget’s disease of bone (PDB) is a chronic focal skeletal disorder that affects 2-3% of the population over the age of 60. PDB is inherited as an autosomal dominant trait with genetic heterogeneity. SQSTM1/p62 UBA domain mutation (p62P392L) is widely identified in PDB and has been shown to increase...
ORGANISM(S): Homo sapiens 
2011-09-30 | E-GEOD-29107 | biostudies-arrayexpress
TranscriptomicsMicroarray Profile of Gene Expression during Osteoclast Differentiation in Modeled Microgravity
Microgravity leads to a 10-15% loss of bone mass in astronauts during space flight. Osteoclast is the multinucleated bone resorbing cell. In this study, we used NASA developed ground based Rotary Wall Vessel Bioreactor (RWV), Rotary Cell Culture System (RCCS) to simulate microgravity (μXg) conditio...
ORGANISM(S): Mus musculus 
2010-04-07 | E-GEOD-21093 | biostudies-arrayexpress
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