Sort   by:  
 Page size 
TranscriptomicsA New Mediator of Singlet Oxygen Responses in Chlamydomonas and Arabidopsis
We identified a small zinc finger protein, MBS, as a new mediator of singlet oxygen responses in Chlamydomonas and Arabidopsis. MBS is required for induction of singlet oxygen-dependent gene expression and, upon oxidative stress, accumulates in distinct granules in the cytosol of Arabidopsis cells....
ORGANISM(S): Arabidopsis thaliana 
2014-04-21 | E-GEOD-49596 | biostudies-arrayexpress
GenomicsBAZ1B in Nucleus Accumbens Regulates Reward-Related Behaviors in Response to Distinct Emotional Stimuli
ATP-dependent chromatin remodeling proteins are being implicated increasingly in the regulation of complex behaviors, including models of several psychiatric disorders. Here, we demonstrate that Baz1b, an accessory subunit of the ISWI family of chromatin remodeling complexes, is upregulated in the n...
ORGANISM(S): Mus musculus 
2016-07-30 | E-GEOD-85005 | biostudies-arrayexpress
GenomicsHistone Arginine Methylation in Cocaine Action: Essential Role of Src Signaling in the Nucleus Accumbens
Despite addiction being one of the most prevalent and debilitating disorders worldwide, effective treatments are lacking. Repeated cocaine exposure induces maladaptive transcriptional regulation within the brainâ??s reward circuitry, such as the nucleus accumbens (NAc), and epigenetic mechanisms, su...
ORGANISM(S): Mus musculus 
2016-08-08 | E-GEOD-85310 | biostudies-arrayexpress
GenomicsEssential role of poly(ADP-ribosyl)ation in cocaine action
Many of the long-term effects of cocaine on the brain's reward circuitry have been shown to be mediated by alterations in gene expression. Several chromatin modifications, including histone acetylation and methylation, have been implicated in this regulation, but the effect of other histone modifica...
ORGANISM(S): Mus musculus 
2014-02-20 | E-GEOD-55136 | biostudies-arrayexpress
Genomicsb-Catenin Mediates the Development of Behavioral Resilience [ChIP-Seq]
Here we show that ?-catenin mediates pro-resilient and anxiolytic effects in mice in the nucleus accumbens (NAc), a key brain reward region, an effect that is mediated by ?-catenin signaling in D2-type medium spiny neurons (MSNs) specifically. Conversely, blocking ?-catenin function in NAc promotes...
ORGANISM(S): Mus musculus 
2014-11-13 | E-GEOD-61294 | biostudies-arrayexpress
UnknownCombining with immunotherapy is an emerging trend for local treatment of colorectal cancer liver metastases: a bibliometric analysis.
Not available
S-EPMC11996661 | biostudies-literature
UnknownGenetic variation of mitochondrial genes among Echinococcus multilocularis isolates collected in western China.
Not available
S-EPMC5450100 | biostudies-literature
Proteomicsphosphoproteomic profile of chicken embryos LC-MS/MS
we evaluated the phosphoproteomic profiles of chicken embryos in pre-diapause, diapause, and reactivated states.
ORGANISM(S): Gallus gallus (Chicken) 
2021-12-16 | PXD029941 | Pride
Embryo Phosphoproteomic Chicken 
TranscriptomicsChemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues [gene expression]
Silencing of genes that suppress the malignant phenotype by DNA methylation spurred an interest in the clinical use of epigenetic reprogramming agents. Single therapy is unlikely to be curative in the context of a heterogeneous disease such as Diffuse Large B cell Lymphomas (DLBCL). The combination ...
ORGANISM(S): Homo sapiens 
2012-07-29 | E-GEOD-28744 | biostudies-arrayexpress
UnknownTherapeutic application of nicotinamide: As a potential target for inhibiting fibrotic scar formation following spinal cord injury.
Not available
S-EPMC11228357 | biostudies-literature
Sort   by:  
 Page size