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TranscriptomicsCharacterization of human malaria parasite Plasmodium falciparum eIF4E homologue and mRNA 5′ cap status
The mRNA 5′ cap is normally essential for eukaryotic mRNA translation, stabilization and transport and both the cap and eIF4E are important elements of post-transcriptional gene regulation. To further our understanding of mRNA translation in the human malaria parasite Plasmodium falciparum, we hav...
ORGANISM(S): Plasmodium falciparum 
2010-06-10 | E-GEOD-6356 | biostudies-arrayexpress
TranscriptomicsInducible knockdown of Plasmodium gene expression using the glmS ribozyme
Conventional reverse genetic approaches for study of Plasmodium malaria parasite gene function are limited, or not applicable. Hence, new inducible systems are needed. Here we describe a method to control P. falciparum gene expression in which target genes bearing a glmS ribozyme in the 3M-bM-^@M-2 ...
ORGANISM(S): Plasmodium falciparum 
2013-09-03 | E-GEOD-43125 | biostudies-arrayexpress
TranscriptomicsMolecular characterization of Plasmodium falciparum Bruno/CELF RNA binding proteins
The human malaria parasite Plasmodium falciparum employs intricate post-transcriptional regulatory mechanisms in different stages of its life cycle. Despite the importance of post-transcriptional regulation, key elements of these processes, namely RNA binding proteins (RBPs), are poorly characterize...
ORGANISM(S): Plasmodium falciparum 
2014-10-23 | E-GEOD-56329 | biostudies-arrayexpress
UnknownImpact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer.
Not available
S-EPMC5903999 | biostudies-literature
TranscriptomicsGlobal gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine
This SuperSeries is composed of the following subset Series: GSE30867: Pyronaridine and chloroquine responses in the K1 strain GSE30869: Comparison of developmental stage transcripts in the K1 strain Refer to individual Series
ORGANISM(S): Plasmodium falciparum 
2011-08-01 | E-GEOD-31109 | biostudies-arrayexpress
TranscriptomicsPlasmodium parasites mount an arrest response against dihydroartemisinin [Microarray]
Control of malaria is threatened by emerging parasite resistance to artemisinin drug (ART) therapies. The molecular details of how Plasmodium malaria parasites response to ART and how this relates to resistance is not clear. To determine how parasites respond to ART by altering gene expression, we p...
ORGANISM(S): Plasmodium falciparum 
2015-10-15 | E-GEOD-61536 | biostudies-arrayexpress
TranscriptomicsPyronaridine and chloroquine responses in the K1 strain
Pyronaridine (PN) and chloroquine (CQ) are structurally related anti-malarial drugs with primarily the same mode of action. However, PN is effective against several multidrug-resistant lines of Plasmodium falciparum, including CQ-resistant lines, suggestive of important operational differences betwe...
ORGANISM(S): Plasmodium falciparum 
2011-08-01 | E-GEOD-30867 | biostudies-arrayexpress
TranscriptomicsComparison of developmental stage transcripts in the K1 strain
To identify the developmentally regulated genes, which could confound identification of PN and CQ drug responsive genes, RNA samples from drug-free synchronized cultures from ring, trophozoite, and schizont stages were individually labelled and hybridized with a pooled sample from the three stages. ...
ORGANISM(S): Plasmodium falciparum 
2011-08-01 | E-GEOD-30869 | biostudies-arrayexpress
GenomicExploring the Genetic Variants Associated with Brain Growth in Children

Understanding the genetic factors that control brain growth during childhood and adolescence is a priority for neuroscience. Its importance lies partly in the finding that disturbances in the course of brain development characterizes many common childhood behavioral problems. Recent advances in n...

phs000962 | dbGaP
ProteomicsEndo_ASPHvariants_APMS_P124_6600
This dataset consists of 10 raw MS files and associated peak lists and results files, acquired on AB Sciex TripleTOF 6600 mass spectrometer operated in Data Dependent Acquisition mode. Samples were generated by Yukari Endo. Mass spectrometry acquisition and data analysis was performed by Cassandra ...
ORGANISM(S): Danio Rerio (ncbitaxon:7955) Homo Sapiens (ncbitaxon:9606) 
2022-05-04 | MSV000089417 | MassIVE
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