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TranscriptomicsTranscriptome of human HT1080 cells treated with purified typhoid toxin in the presence and absence of serum
Aim of the experiment: To examine changes in gene expression in HT1080 fibroblasts following treatment with purified recombinant wild-type typhoid toxin (WT-tox) from Salmonella Typhi relative to a mutant H160Q variant lacking DNase activity (HQ-tox), in the presence and absence of serum. The toxin ...
ORGANISM(S): Homo sapiens 
2025-06-01 | E-MTAB-15046 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Troy positive gastric cells
Proliferation of the self-renewing epithelium of the gastric corpus occurs almost exclusively in the isthmus of the glands, from where cells migrate bi-directionally towards pit and base. The isthmus is therefore generally viewed as the stem cell zone. We find that the stem cell marker Troy is expre...
ORGANISM(S): Mus musculus 
2013-10-23 | E-GEOD-44060 | biostudies-arrayexpress
TranscriptomicsCOMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS
This SuperSeries is composed of the following subset Series: GSE23672: COMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AGILENT ARRAYS) GSE33948: COMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AFFYMETRIX ARRAYS...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-33949 | biostudies-arrayexpress
TranscriptomicsCOMPARATIVE TRANSCRIPTOMIC AND PROTEOMIC ANALYSIS OF LGR5+ve STEM CELLS AND THEIR DAUGHTERS (AFFYMETRIX ARRAYS)
The identification of Lgr5 as an intestinal stem cell marker has made it possible to isolate and study primary intestinal stem cells. Applying quantitative mass spectrometry as well as transcriptomic analysis, we profiled the protein and gene changes between FACS-sorted Lgr5+ve stem cells and their ...
ORGANISM(S): Mus musculus 
2012-08-12 | E-GEOD-33948 | biostudies-arrayexpress
TranscriptomicsCRISPR screen exploring resistance to AKTi (Capivasertib) in ER+ Breast Cancer in MCF7, T47D and CAMA-1 cell lines
A genome-wide CRISPR-Cas9 knockout screen was performed in the breast cancer cell lines T47D, MCF7, and CAMA-1 to identify genes modulating sensitivity and resistance to capivasertib, a selective AKT inhibitor. Cells were transduced with a CRISPR library, followed by treatment with capivasertib or v...
ORGANISM(S): Homo sapiens 
2026-05-25 | E-MTAB-16438 | biostudies-arrayexpress
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
UnknownGut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients.
Not available
S-EPMC5827966 | biostudies-literature
TranscriptomicsRNA-seq of human THP-derived macrophages stimulated with neutrophil extracellular traps (NETs)
To investigate the effects of neutrophil extracellular traps (NETs) on human THP-1-derived macrophages, cells were left untreated or stimulated for 4 h with NETs, either alone or in combination with the TLR4 inhibitor CLI-095 (5 µM). Each condition included three independent biological replicates.
ORGANISM(S): Homo sapiens 
2026-10-27 | E-MTAB-17568 | biostudies-arrayexpress
UnknownObesity Is Associated with Altered Tumor Metabolism in Metastatic Melanoma.
Not available
S-EPMC10311539 | biostudies-literature
UnknownTwo Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease.
Not available
S-EPMC10794000 | biostudies-literature
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