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ProteomicsA Derivatization-Free PRM Workflow for Quantitative, Site-Specific Analysis of Histone Post-Translational Modifications
Histone post-translational modifications (PTMs) are key regulators of chromatin architecture and gene expression. Although DIA-based platforms for histone PTM quantification are available, multiplexed targeted assays remain underdeveloped. In addition, bottom-up workflows frequently rely on chemical...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2026-09-09 | PXD071393 | Pride
Ptms Prm Skyline Quantitation Histone Argc 
MetabolomicsER stress inhibits liver fatty acid oxidation while unmitigated stress leads to anorexia-induced lipolysis and both liver and kidney steatosis
The unfolded protein response (UPR), induced by endoplasmic reticulum (ER) stress, regulates the expression of factors that restore protein folding homeostasis. However, in the liver and kidney, ER stress also leads to lipid accumulation, accompanied at least in the liver by transcriptional suppress...
2017-06-23 | MTBLS472 | MetaboLights
UnknownMeta-analysis of Parkinson's disease: identification of a novel locus, RIT2.
Not available
S-EPMC3354734 | biostudies-literature
UnknownMulticentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery.
Not available
S-EPMC4973675 | biostudies-literature
UnknownSearch for supersymmetry in pp collisions at [Formula: see text] TeV in events with a single lepton, jets, and missing transverse momentum.
Not available
S-EPMC4370766 | biostudies-literature
UnknownChallenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives.
Not available
S-EPMC6909648 | biostudies-literature
UnknownImpact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study.
Not available
S-EPMC8759520 | biostudies-literature
UnknownValidation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery.
Not available
S-EPMC8855527 | biostudies-literature
UnknownElective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries.
Not available
S-EPMC9621702 | biostudies-literature
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