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MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
MetabolomicsUntargeted serum metabolomics of early-life antibiotic intervention, fecal microbiota transplantation restoration, and short-term high-fat diet effects in C57BL/6 mice
This study profiles the serum metabolome in C57BL/6 mice subjected to early-life antibiotic treatment (vancomycin and gentamicin, 2 weeks), followed by fecal microbiota transplantation and a short-term high-fat diet. Serum samples were collected longitudinally and analyzed by liquid chromatography-t...
2026-08-20 | MTBLS14801 | MetaboLights
ProteomicsPredictive Value of Proteomic Markers for Advanced Rectal Cancer with Neoadjuvant Chemoradiotherapy
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032117 |
ProteomicsProteomic and transcriptome analysis of DIA protein in Morchella edulis
In proteomics, DIA technology, as a high-throughput and high-sensitivity protein detection technique, can comprehensively and accurately identify and quantify proteins in samples. For morel mushrooms, DIA proteomic analysis can provide a deeper understanding of their protein composition, structure, ...
ORGANISM(S): Morchella Sextelata 
2024-11-25 | PXD058217 |
UnknownGenomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication.
Not available
S-EPMC2699053 | biostudies-literature
ProteomicsProtein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
The MS data of Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
ORGANISM(S): Homo Sapiens 
2019-12-11 | PXD016712 |
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD045174 |
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