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We explored the hypothesis that adipose tissue contains epigenetically distinct subpopulations of adipocytes that are differentially potentiated to record cellular memories of their environment. Adipocytes are large, fragile, and technically difficult to efficiently isolate and fractionate. We devel...
ORGANISM(S): Sus scrofa 
Our previous study (Environ Pollut. 2023;323:121307) has indicated that Glucose-dependent insulinotropic polypeptide receptor (GIPR) is down-regulated in periodontal ligament stem cells (PDLSCs) by cigarette and E-cig. In the current study, ChIP-seq was conducted to study the genome-wide occupancies...
ORGANISM(S): Homo sapiens 
Meiotic recombination ensures proper chromosome segregation and genetic diversity during gametogenesis, and its disruption leads to infertility. It is known that the dual histone methylation writer–reader system, in which PRDM9 deposits H3K4me3 and H3K36me3 marks at nucleosomes to specify recombinat...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2026-01-07 | PXD068838 | Pride
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