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TranscriptomicsMicroarray profiling analysis in Jmj-Fl/Fl and Jmj-null ESCs.
We used microarrays to detail the role of JMJ in ES cell function. Keywords: cell type and time course Cells were harvested for RNA extraction and hybridization on Affymetrix microarrays.
ORGANISM(S): Mus musculus 
2009-12-29 | E-GEOD-19165 | biostudies-arrayexpress
Transcriptomicscis regulated role of lncRNA in transcriptional or developmental process (ChIRP-Seq)
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-79541 | biostudies-arrayexpress
TranscriptomicsEvx1as and EVX1 knockouts by CRISPR
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-70419 | biostudies-arrayexpress
TranscriptomicsOpposing roles for the lncRNA Haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation
Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific lncRNAs, and the molecular mechanisms through which they act, remain unclear. Here, we demonstrate discrete and opposing roles for the lncRNA tra...
ORGANISM(S): Mus musculus 
2015-04-20 | E-GEOD-58514 | biostudies-arrayexpress
ProteomicsDistinct peptide profiles in human dura of CSDH
Whether dura mater derived endogenous peptides participate in the pathogenesis of CSDH remains undetermined. In the current study, the peptidomic profiles were performed in human dura of CSDH (three patients) and the relative control group (three non-CSDH samples) by LC-MS (liquid chromatography–mas...
ORGANISM(S): Homo Sapiens 
2023-10-25 | PXD046368 |
ProteomicsDistinct peptide profiles in CPZ-induced mouse
Here we performed peptidomic analysis of freshly isolated corpus callosum (CC) from the brains of CPZ-treated mice and normal diet controls of male C57BL/6 mice by LC-MS/MS. Identified a total of 217 peptides were expressed at different levels in MS mice model compared with controls.
ORGANISM(S): Mus Musculus 
2023-07-03 | PXD043468 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
2020-07-30 | PXD020653 |
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