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ProteomicsQuantitative Proteomics Benchmark Dataset to evaluate label-free quantitative methods- LC/Orbitrap Fusion MS analysis of E coli proteomes spiked-in Human proteins at 5 different levels (N=20)
To unbiasedly evaluate the quantitative performance of different quantitative methods, and compare different popular proteomics data processing workflows, we prepared a benchmark dataset where the various levels of spikeed-in E. Coli proteome that true fold change (i.e. 1 fold, 1.5 fold, 2 fold, 2....
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2018-05-16 | PXD003881 | Pride
Human Label-free Ionstar Ecoli Benchmark Orbitrap fusion 
ProteomicsIn-depth and reproducibly quantitation of benchmark dataset consiting of 20 files
We prepared a benchmark dataset where the various levels of spikeed-in E. Coli proteome that true fold change (i.e. 1 fold, 1.5 fold, 2 fold, 2.5 fold and 3 fold) and true identities of positives/negatives (i.e. E.Coli proteins are true positives while Human proteins are true negatives) are known. T...
ORGANISM(S): Homo sapiens (Human) 
2017-04-20 | PXD005590 | Pride
Lc-ms Human E.coli 
ProteomicsHuman pancreatic cancer LC-MSMS
Despite decades of effort, pancreatic adenocarcinoma (PDAC) remains an intractable clinical challenge. An insufficient understanding of mechanisms underlying tumor cell responses to chemotherapy contributes significantly to the lack of effective treatment regimens. Here, paclitaxel, a first-line che...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082878 | MassIVE
GenomicsGadd45a promotes DNA demethylation through TDG
Growth arrest and DNA-damage-inducible protein 45 (Gadd45) family members have been implicated in DNA demethylation in vertebrates. However, it remained unclear how they contribute to the demethylation process. Here, we demonstrate that Gadd45a promotes active DNA demethylation through thymine DNA g...
ORGANISM(S): Mus musculus 
2015-05-07 | E-GEOD-62496 | biostudies-arrayexpress
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