Sort   by:  
 Page size 
GenomicsIdentification of Hnf6 binding sites in male and female mouse liver
∼40,000 HNF6 binding sites were identified in mouse liver chromatin, including several thousand sites showing significant differences in level of HNF6 binding between male and female mouse liver. These sex-biased HNF6 binding sites showed strong enrichment for sex-biased DNase hypersensitive sites a...
ORGANISM(S): Mus musculus 
2015-07-28 | E-GEOD-60014 | biostudies-arrayexpress
TranscriptomicsImpact of Cux2 knockdown on gene expression in female mouse liver (Mus musculus)
We identified genes expressed in mouse liver that are regulated by Cux2, a highly female-specific liver transcription factor whose expression is regulated by sex-dependent plasma GH patterns. Using siRNA to knockdown Cux2 expression in female liver, we show that female specific genes are predominan...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-37078 | biostudies-arrayexpress
TranscriptomicsImpact of Cux2 overexpression on gene expression in male and female mouse liver (Mus musculus)
We identified genes expressed in mouse liver that are regulated by Cux2, a highly female-specific liver transcription factor whose expression is regulated by sex-dependent plasma GH patterns. Using adenovirus to overexpress Cux2 (Adeno-Cux2) in male liver, we show that Cux2 represses ~35% of male-b...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-35897 | biostudies-arrayexpress
GenomicsIdentification of Cux2 binding sites in female and male mouse liver
Growth hormone (GH)-regulated transcription factors, notably STAT5 and BCL6, play a major role in regulating genes showing sex differences in expression in mouse liver, primarily through their effects in male liver, where male-biased genes are up regulated and many female-biased genes are actively r...
ORGANISM(S): Mus musculus 
2012-09-10 | E-GEOD-35985 | biostudies-arrayexpress
UnknownSynthesis of a Truncated Microcystin Tetrapeptide Molecule from a Partial Mcy Gene Cluster in Microcystis Cultures and Blooms.
Not available
S-EPMC11647769 | biostudies-literature
ProteomicsQuantitative Measurement of the Requirement of Diverse Protein Degradation Pathways in MHC Class I Peptide Presentation
The adaptive immune system distinguishes self from non-self by surveying peptides generated from degradation of intracellular proteins that are loaded onto MHC Class I molecules for display on the cell surface. While early studies reported that the bulk of cell surface MHC Class I complexes require ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-02-15 | MSV000091285 | MassIVE
GenomicsCIDR: Genome Wide Association Study in Familial Parkinson Disease (PD)

This proposal brings together the two largest NIH funded genetic studies focused on the identification of novel genes that influence the risk of PD. These two studies, PROGENI (PI: Tatiana Foroud; R01NS037167) and GenePD (PI: Richard Myers; R01NS036711) have been evaluating and recruiti...

phs000126.v1.p1 | EGA
UnknownType 2 immune responses are associated with less severe COVID-19 in a hospitalized cohort.
Not available
S-EPMC12284355 | biostudies-literature
UnknownHost-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
Not available
S-EPMC11723965 | biostudies-literature
UnknownPhenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
Not available
S-EPMC9359694 | biostudies-literature
Sort   by:  
 Page size