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TranscriptomicsKDM5C safeguards the appropriate timing of early neurodevelopment
We generated human induced pluripotent cells from intellectual disability patients carrying the c.2T>C mutation in KDM5C (Called “Mutant”). We generated a paired, isogenic human iPS cell line (called “Corrected”) using CRISPR/Cas9 and PiggyBac gene-editing technologies and conducted neuronal differe...
ORGANISM(S): Homo sapiens 
2023-10-13 | E-MTAB-7551 | biostudies-arrayexpress
ProteomicsA pipeline that integrates the discovery and verification of plasma protein biomarkers reveals candidate markers for cardiovascular disease
Addona TA, Shi X, Keshishian H, Mani DR, Burgess M, Gillette MA, Clauser KR, Shen D, Lewis GD, Farrell LA, Fifer MA, Sabatine MS, Gerszten RE, Carr SA. Nat Biotechnol. 2011, 29(7):635-43. doi: 10.1038/nbt.1899. PMCID:PMC3366591. Discovery, AIMS, and MRM datasets Discovery_Tranche_hash: b/quYtp/Q8fY...
2013-12-19 | MSV000078513 | MassIVE
UnknownHNO to NO Conversion Mechanism with Copper Zinc Superoxide Dismutase, Comparison with Heme Protein Mediated Conversions, and the Origin of Questionable Reversibility.
Not available
S-EPMC7954974 | biostudies-literature
ProteomicsQuantitative Proteome Responses to Oncolytic Reovirus in GM-CSF and M-CSF-Differentiated Bone Marrow-Derived Cells
To explore reovirus-macrophage interactions, we performed tandem mass tag (TMT)-based quantitative temporal proteomics on mouse bone marrow-derived macrophages (BMMs) generated with 2 cytokines, M-CSF and GM-CSF, representing anti- and pro-inflammatory macrophages, respectively. We quantified 6,863 ...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-07 | PXD015203 | Pride
Reovirus Cell differentiation Macrophages Oncolytic viruses Antigen presentation/processing Viral defense Quantitative proteomics Anti-viral immune response 
TranscriptomicsRole of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation (RNA-seq)
Cancer cells frequently depend on chromatin regulatory activities to maintain a malignant phenotype. Here, we show that leukemia cells require the mammalian SWI/SNF chromatin remodeling complex for their survival and aberrant self-renewal potential. While Brg1, an ATPase subunit of SWI/SNF, is known...
ORGANISM(S): Mus musculus 
2013-12-02 | E-GEOD-52623 | biostudies-arrayexpress
UnknownDifferential Item Functioning and Clinical Utility of the Subjective Memory Complaints Questionnaire in a Multi-Ethnic Cohort.
Not available
S-EPMC11930848 | biostudies-literature
UnknownRacial and ethnic differences in sleep-disordered breathing and sleep duration among stroke patients.
Not available
S-EPMC9802657 | biostudies-literature
UnknownPUFA ω-3 and ω-6 biomarkers and sleep: a pooled analysis of cohort studies on behalf of the Fatty Acids and Outcomes Research Consortium (FORCE).
Not available
S-EPMC8895226 | biostudies-literature
UnknownMDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma.
Not available
S-EPMC7859402 | biostudies-literature
UnknownUnsteady Magnetopause Reconnection Under Quasi-Steady Solar Wind Driving.
Not available
S-EPMC9285935 | biostudies-literature
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