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MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
UnknownThe level of moral sensitivity among nurses: a systematic review and meta-analysis.
Not available
S-EPMC11938698 | biostudies-literature
TranscriptomicsASC controls T-bet-dependent CTL differentiation and defines transplant outcome independent of the inflammasome
The adaptor protein ASC is known to facilitate caspase-1 activation essential for innate host immunity via the formation of the inflammasome complex - a multi-protein structure responsible for processing IL-1beta and IL-18 to their active moieties. Here we demonstrate that ASC-deficient CD8+ T cell...
ORGANISM(S): Mus musculus 
2016-04-01 | E-GEOD-78755 | biostudies-arrayexpress
Transcriptomicssetdb2 knockdown microarray
As the primary driving forces of gastrulation, convergence and extension (C&E) movements lead to a medio-lateral narrowing and an anterior-posterior elongation of the embryonic body axis. Histone methylation as a post-translational modification plays a critical role for early embryonic development, ...
ORGANISM(S): Danio rerio 
2014-06-20 | E-MTAB-2207 | biostudies-arrayexpress
UnknownSpecies Quantification in Complex Herbal Formulas-Vector Control Quantitative Analysis as a New Method.
Not available
S-EPMC7725679 | biostudies-literature
ProteomicsDetermination of proteins labeling by Turbo-ID in PIGS-HRD1-CD55-TKO cells
To identify proteins that might physically interact with CD55
ORGANISM(S): Homo sapiens (Human) 
2023-02-19 | PXD028707 | Pride
Erad Gpi anchored protein Cd55 
UnknownBlockade of mitochondrial components release by exosome pathway promotes the pathogenesis of Fuchs endothelial corneal dystrophy.
Not available
S-EPMC12811314 | biostudies-literature
TranscriptomicsRNA-seq of human adipose-derived mesenchymal stem cells cultured in hypoxia against normoxia controls, and human tympanic membrane keratinocytes
Human adipose-derived mesenchymal stem cells were cultured either in hypoxia (Hx; <0.1% oxygen) or standard culture conditions (normoxia, Nx) over 48 hours in serum-free medium. Human tympanic membrane keratinocytes were cultured in standard culture conditions over 48 hours in serum-free medium.
ORGANISM(S): Homo sapiens 
2022-03-31 | E-MTAB-9979 | biostudies-arrayexpress
UnknownEfficacy and safety of Xiangsha Liujunzi granules for functional dyspepsia: A multi-center randomized double-blind placebo-controlled clinical study.
Not available
S-EPMC5558122 | biostudies-literature
UnknownAlterations of conjunctival microbiota associated with orthokeratology lens wearing in myopic children.
Not available
S-EPMC10717905 | biostudies-literature
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