Sort   by:  
 Page size 
TranscriptomicsExpression data from brain, liver and spleen of Npc1-/- mice
Niemann-Pick Type C (NPC) disease is a rare, genetic, lysosomal disorder with progressive neurodegeneration. Poor understanding of the pathophysiology and lack of blood-based diagnostic markers are major hurdles in the treatment and management of NPC and several additional neurological, lysosomal di...
ORGANISM(S): Mus musculus 
2012-12-27 | E-GEOD-39621 | biostudies-arrayexpress
TranscriptomicsExpression data from control siRNA and M-NM-2-catenin siRNA transfected cultured mouse dermal cells
M-NM-2-catenin activity of dermal cells is crucial for hair follicle neogenesis and strongly suggest that transcriptional target genes of M-NM-2-catenin pathway are essential for maintaining trichogenicity of dermal cells. We used microarrays to identify genes targeted by the M-NM-2-catenin pathway ...
ORGANISM(S): Mus musculus 
2013-09-03 | E-GEOD-50525 | biostudies-arrayexpress
TranscriptomicsA Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development
Bone Morphogenetic Proteins (BMPs), a subgroup of the TGF- superfamily, were originally isolated from bone on the basis of their ability to induce ectopic bone development. While BMPs are involved in a wide range of developmental and physiological functions, very few vertebrate target genes in t...
ORGANISM(S): Xenopus laevis 
2010-06-10 | E-GEOD-2274 | biostudies-arrayexpress
TranscriptomicsGene expression profile of human epidermoid carcinoma KB cells that overexpress thymidine phosphorylase
Thymidine phosphorylase (TP) catalyzes the reversible phosphorolysis of thymidine, deoxyuridine, and their analogs to the respective bases and 2-deoxy-D-ribose-1-phosphate. TP is identical to platelet-derived endothelial cell growth factor (PD-ECGF). TP was reported to induce many angiogenic factors...
ORGANISM(S): Homo sapiens 
2014-08-03 | E-GEOD-31467 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of psychostimulant reinforcement in rats
Drug-induced alterations in transcriptional regulation play a central role in establishing the persistent neuroplasticities that occur during drug addiction. Additionally, changes in gene expression associated with drug administration provide valuable insight into the molecular basis of drug abuse. ...
ORGANISM(S): Rattus norvegicus 
2013-06-27 | E-GEOD-43748 | biostudies-arrayexpress
ProteomicsIdentification of Novel Auto-antibodies in Type 1 Diabetic Patients using a High-density Protein Microarray
Type 1 diabetes mellitus (T1DM) results from immune mediated destruction of pancreatic beta cells. However, clinical and immunologic phenotypes of T1DM are variable. Several auto-antibodies including GADA, IA-2A, and ZnT8A, were identified in T1DM, but the prevalence of these auto-antibodies varied ...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-50866 | biostudies-arrayexpress
TranscriptomicsIdentification of neural genes using Xenopus DNA microarrays
In order to isolate novel genes regulating neural induction, we utilized a DNA microarray approach. As neural induction is thought to occur via the inhibition of BMP signaling, BMP signaling was inhibited in ectodermal cells by overexpression of a dominant-negative receptor. RNAs were isolated from...
ORGANISM(S): Xenopus laevis 
2010-06-10 | E-GEOD-2266 | biostudies-arrayexpress
TranscriptomicsSingle Cell based genomewide gene expression analysis of murine bone-marrow derived Very Small Embryonic-Like Stem Cells (VSELs)
Recently, we identified a population of Oct4+Sca-1+Lin-CD45- very small embryonic-like stem-cells (VSELs) in adult tissues. Open chromatin structure of pluripotency genes and genomic imprinting-related epigenetic mechanisms maintain pluripotency and quiescence of VSELs, respectively. However, global...
ORGANISM(S): Mus musculus 
2011-12-21 | E-GEOD-29281 | biostudies-arrayexpress
UnknownFactors associated with D-dimer levels in HIV-infected individuals.
Not available
S-EPMC3953205 | biostudies-literature
MetabolomicsUnveiling molecular changes in guabiju during Aspergillus brasiliensis cultivation: insights from untargeted metabolomics

Black aspergilli exhibit remarkable bioconversion potential by transforming plant matrices into bioactive compounds, although their metabolic processes remain underexplored. This study investigated the biotransformation of metabolites during the solid-state cultivation of guabiju (Myrcianthes...

2025-08-08 | MTBLS12436 | MetaboLights
Sort   by:  
 Page size