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ProteomicsHuman lung cancer TMT-labeling LC-MS
Although the paradigm of cancer treatment has changed with the recent development of drugs targeting immune checkpoints (PD-1, PD-L1, etc.), there is still a need for new targets for anticancer drugs. To discover new potential targets for immunotherapy, we compared membrane protein expression in non...
ORGANISM(S): Homo sapiens (Human) 
2024-01-08 | PXD044086 | Pride
Tmt-labeling lc-ms Immune checkpoint Human lung cancer Membrane protein 
TranscriptomicsTo identify gene markers which differentiate between AERD and ATA with a high discriminative power.
Aspirin-exacerbated respiratory disease (AERD) has association with severe asthma and aspirin can cause asthma to worsen, often in the form of a severe and sudden attack. The oral aspirin challenge (OAC) is the gold standard to confirm the diagnosis of AERD but it is time consuming and produces seri...
ORGANISM(S): Homo sapiens 
2013-04-08 | E-GEOD-45847 | biostudies-arrayexpress
ProteomicsCntnap2 KO mouse mPFC proteome for ASD
Autism Spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder where patients have impaired social behavior and communication, and restricted interests. Although various studies have been carried out to unveil the mechanisms associated with ASD, its pathophysiology is still poorly und...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD031656 | Pride
Cntnap2 Mpfc Mouse 
TranscriptomicsGene expression profiles of T cell fraction enriched for donor antigen-reactive T cells in skin allografted recipient mice (II)
Measurement of specific gene expression in clinical samples is a promising approach for monitoring the recipient immune status to the graft in organ transplantation. Identification of biomarker genes closely associated with tolerance or rejection is critical for this monitoring protocol. Unlike prev...
ORGANISM(S): Mus musculus 
2011-10-12 | E-GEOD-32953 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of T cell fraction enriched for donor antigen-reactive T cells in skin allografted recipient mice (I)
Measurement of specific gene expression in clinical samples is a promising approach for monitoring the recipient immune status to the graft in organ transplantation. Identification of biomarker genes closely associated with tolerance or rejection is critical for this monitoring protocol. Unlike prev...
ORGANISM(S): Mus musculus 
2011-10-12 | E-GEOD-32952 | biostudies-arrayexpress
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