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Unknownp38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin.
Not available
S-EPMC6894093 | biostudies-literature
TranscriptomicsThe translational landscape of mTOR signaling steers cancer initiation and metastasis
The mammalian target of rapamycin (mTOR) kinase is a master regulator of protein synthesis that couples nutrient sensing to cell growth and cancer. However, the downstream translationally regulated nodes of gene expression that may direct cancer development are poorly characterized. Employing riboso...
ORGANISM(S): Homo sapiens 
2012-02-28 | E-GEOD-35469 | biostudies-arrayexpress
UnknownDirect Modulators of K-Ras-Membrane Interactions.
Not available
S-EPMC10510109 | biostudies-literature
UnknownEscape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3.
Not available
S-EPMC3025857 | biostudies-literature
ProteomicsTargeting Ras-, Rho-, and Rab-Family GTPases via a Conserved Cryptic Pocket
The family of Ras-like GTPases consists of over 150 different members, regulated by an even larger number of guanine exchange factors (GEFs) and GTPase-activating proteins (GAPs) which comprise cellular switch networks that govern cell motility, growth, polarity, protein trafficking, and gene expres...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054414 | Pride
Gtpase 
UnknownTargeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket.
Not available
S-EPMC11531380 | biostudies-literature
UnknownCyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II.
Not available
S-EPMC3746743 | biostudies-literature
UnknownComprehensive analysis of T cell leukemia signals reveals heterogeneity in the PI3 kinase-Akt pathway and limitations of PI3 kinase inhibitors as monotherapy.
Not available
S-EPMC5969748 | biostudies-literature
UnknownA Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.
Not available
S-EPMC5386178 | biostudies-literature
ProteomicsKinase peptide discovery in MIB enriched samples using 2m monolithic silica-C18 column
This dataset accompanies our publication "An optimized chromatographic strategy for multiplexing in parallel reaction monitoring mass spectrometry: Insights from quantitation of activated kinases" in Molecular & Cellular Proteomics, 2016 (https://www.ncbi.nlm.nih.gov/pubmed/27940637). The submitted ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-10 | MSV000079644 | MassIVE
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