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TranscriptomicsEffects of Rituximab on global gene expression profiles in the RA synovium
Objective: Rituximab displays therapeutic benefits in the treatment of rheumatoid arthritis (RA) patients resistant to TNF blockade. However, the precise role of B cells in the pathogenesis of RA is still unknown. In this study we investigated the global molecular effects of rituximab in synovial bi...
ORGANISM(S): Homo sapiens 
2010-10-19 | E-GEOD-24742 | biostudies-arrayexpress
TranscriptomicsThe Arabidopsis spaceflight transcriptome: a comparison of whole plants to discrete root, hypocotyl and shoot responses to the orbital environment
Arabidopsis thaliana was evaluated for its response to the spaceflight environment in three replicated experiments on the International Space Station. Two approaches were used; GFP reporter genes were used to collect gene expression data in real time within unique GFP imaging hardware, and plants we...
ORGANISM(S): Arabidopsis thaliana 
2013-10-04 | E-MTAB-1264 | biostudies-arrayexpress
TranscriptomicsRho directs widespread termination of intragenic and stable RNA transcription
The transcription termination factor Rho is a global regulator of RNA polymerase (RNAP). Although individual Rho-dependent terminators have been studied extensively, less is known about the sites of RNAP regulation by Rho on a genome-wide scale. Using chromatin immunoprecipitation and microarrays (...
ORGANISM(S): Escherichia coli 
2010-05-18 | E-GEOD-16562 | biostudies-arrayexpress
ProteomicsA salivary GMC oxidoreductase of Manduca sexta re-arranges the green leaf volatile profile of its host plant
Green leaf volatiles (GLVs) are short-chain oxylipins that are emitted from plants in response to stress. Previous studies have shown that oral secretions (OS) of the tobacco hornworm Manduca sexta, introduced into plant wounds during feeding, catalyze the re-arrangement of GLVs from Z-3- to E-2-iso...
ORGANISM(S): Manduca Sexta (ncbitaxon:7130) 
2023-05-23 | MSV000092011 | MassIVE
GenomicsMapping and dynamics of regulatory DNA in A. thaliana tissues and cell types across developmental transitions
We performed DNase-seq on root tissue, root epidermal cell types, seed coat epidermal cells at two developmental stages, and open and closed flowers. Root: We performed chromatin profiling (DNase-seq) on whole root (all cell types), or root epidermal cell types (hair cell, non-hair cell). Seed coat:...
ORGANISM(S): Arabidopsis thaliana 
2013-12-15 | E-GEOD-53324 | biostudies-arrayexpress
UnknownThe Evolving Role of Short-Term Professional Continuous Glucose Monitoring on Glycemic Control and Hypoglycemia Among Saudi Patients with Type 1 Diabetes: A Prospective Study.
Not available
S-EPMC4575306 | biostudies-literature
UnknownCase series of high-risk percutaneous coronary intervention with rotational atherectomy under short-term mechanical circulatory support with TandemHeart in the setting of acute myocardial infarction.
Not available
S-EPMC7780489 | biostudies-literature
GenomicsThe Hippo tranducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation
The Hippo pathway effector YAP1 controls stem cell fate in epithelial tissues, but its role in stem cells of non-epithelial tissues, such as skeletal muscle, is poorly documented. Here we show that sustained YAP1 activity in mouse activated satellite cells in vivo induces rhabdomyosarcoma (RMS) rese...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-55186 | biostudies-arrayexpress
UnknownThe ancient mariner sails again: transposition of the human Hsmar1 element by a reconstructed transposase and activities of the SETMAR protein on transposon ends.
Not available
S-EPMC1900042 | biostudies-literature
TranscriptomicsEpigenome analysis of alcohol consumption in lymphocyte cell (LC) samples
Genome-wide DNA methylation profiling of individuals consuming alcohol and controls in LC samples. Individuals consuming alcohol were profiled at time of intake (T1) into treatment facility and four weeks into treatment (T2). Controls were profiled once. The Illumina Infinium 450k Human DNA Methylat...
ORGANISM(S): Homo sapiens 
2014-09-24 | E-GEOD-57853 | biostudies-arrayexpress
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