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ProteomicsSHP-1(FLAG) AP-MS, with/without TAOK3 and/or SRC kinase
To understand the influence of phosphorylation on the protein-protein interactions, we performed an AP-MS of SHP-1(FLAG) in HEK293T/17 cells co-transfected with TAOK3 and/or SRC kinase. Whilst TAOK3 phosphorylates Thr-394, SRC phosphorylates Tyr536 and Tyr564.
ORGANISM(S): Homo sapiens (Human) 
2024-01-04 | PXD042497 | Pride
Ap-ms Shp-1(flag) Ppis Taok3 Phosphorylation Src 
TranscriptomicsGene expression-based, six individualized outcomes for cancer cells treated by TMEFF2 adenovirus and 2837 genes changes after treatment.
The genes expression changes after the adenovirus treatment for 36 hours In this study, the three control groups and three treatment groups were used to acquire expression profiles
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-49049 | biostudies-arrayexpress
TranscriptomicsTMEFF2 treated cancer cells and gastric cancer
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-10-01 | E-GEOD-49052 | biostudies-arrayexpress
UnknownFarnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice.
Not available
S-EPMC6033648 | biostudies-literature
TranscriptomicsTranscription profiling of mouse wild type adult male mouse livers vs transgenic mice expressing human Small Heterodimer Partner in hepatocytes
Comparison of gene expression in adult male mouse livers between wildtype mice and Transgenic mice expressing human Small Heterodimer Partner in hepatocytes.
ORGANISM(S): Mus musculus 
2006-01-01 | E-MEXP-294 | biostudies-arrayexpress
TranscriptomicsSMAUG is required for zygotic transcription during the maternal-zygotic transition MZT
Microarray analysis of zygotic gene expression in 2-to-3 hour wild-type (wt) and smg mutant embryos. Expression is relative to mature, stage 14 oocytes, which contain the full maternal pool of mRNA. Strictly maternal genes that are not transcribed at the MZT contribute approximately 80% of transc...
ORGANISM(S): Drosophila melanogaster 
2010-06-19 | E-GEOD-13287 | biostudies-arrayexpress
TranscriptomicsmiR-309-dependent unstable maternal mRNAs are stabilized in smaug mutants
The behavior of 410 miR-309-dependent maternal mRNAs (from Bushati et al., 2008) in embryos from wild type and smg-mutant females relative to wild-type stage 14 oocyte reference RNA. All are unstable in wild-type while almost 85% are stabilized in smg mutants mRNA was extracted from staged embryos a...
ORGANISM(S): Drosophila melanogaster 
2010-06-19 | E-GEOD-13288 | biostudies-arrayexpress
TranscriptomicsSRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer
The neuroendocrine (NE) phenotype is associated with the development of metastatic castration-resistant prostate cancer (CRPC). Our objective was to characterize the molecular features of the NE phenotype in CRPC. Expression of chromogranin A (CHGA), synaptophysin (SYP), androgen receptor (AR), and ...
ORGANISM(S): Homo sapiens 
2015-06-24 | E-GEOD-66187 | biostudies-arrayexpress
ProteomicsGeneral Approach for Tetramer Based Identification of Autoantigen Reactive B Cells: Characterization of La and snRNP Reactive B Cells in Autoimmune BXD2 Mice
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-02-28 | E-GEOD-65290 | biostudies-arrayexpress
TranscriptomicsAge-Dependent Differences in Gene Expression in Response to Calvarial Injury
Children less than 2 years of age are capable of healing large calvarial defects, whereas adults have been found to lack this endogenous ability. In this study, we used microarray analysis to compare genomewide expression patterns during active regeneration after injury with calvaria in skeletally i...
ORGANISM(S): Mus musculus 
2009-01-14 | E-GEOD-14424 | biostudies-arrayexpress
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