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ProteomicsSHP-1(FLAG) AP-MS, with/without TAOK3 and/or SRC kinase
To understand the influence of phosphorylation on the protein-protein interactions, we performed an AP-MS of SHP-1(FLAG) in HEK293T/17 cells co-transfected with TAOK3 and/or SRC kinase. Whilst TAOK3 phosphorylates Thr-394, SRC phosphorylates Tyr536 and Tyr564.
ORGANISM(S): Homo sapiens (Human) 
2024-01-04 | PXD042497 | Pride
Ap-ms Shp-1(flag) Ppis Taok3 Phosphorylation Src 
GenomicsGene array analysis of WT and TAOK3 KO T cells
Gene array analysis of WT and TAOK3 KO T cells
PRJNA478001 | ENA
UnknownSTE20-type kinase TAOK3 regulates hepatic lipid partitioning.
Not available
S-EPMC8567304 | biostudies-literature
ProteomicsTAOK3 controls naïve T cell homeostasis
Genetic deletion or kinase inactivation of TAOK3 resulted in a profound, cell-intrinsic loss of naive CD8⁺ T cells. Despite enhanced sensitivity to TCR ligation and enhanced downstream signalling, proliferating CD8⁺ T cells did not survive in vitro and anti-viral CD8⁺ T cell immunity was compromised...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-02 | PXD077760 | Pride
Ste20 kinase Tcr signaling Naïve t cells Phospho-proteomics 
UnknownSTE20 kinase TAOK3 regulates type 2 immunity and metabolism in obesity.
Not available
S-EPMC10287548 | biostudies-literature
UnknownTAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization.
Not available
S-EPMC7494564 | biostudies-literature
UnknownKnockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice.
Not available
S-EPMC10589923 | biostudies-literature
UnknownTAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα.
Not available
S-EPMC10316641 | biostudies-literature
UnknownKinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway.
Not available
S-EPMC7579951 | biostudies-literature
UnknownTAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM.
Not available
S-EPMC10582451 | biostudies-literature
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