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Small hepatocyte-like progenitor cells (SHPCs) are hepatocytic progenitor cells that transiently form clusters in rat livers treated with retrorsine and with 70% partial hepatectomy (PH). We previously reported that transplantation of Thy1+ cells derived from D-galactosamine-treated livers promotes ...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-04-07 | PXD039384 | Pride
Small hepatocyte progenitor cells (SHPCs) can be derived from primary adult human hepatocytes on mouse embryonic fibroblasts (MEFs). SHPCs derived and cultured on MEFs retain their differentiated morphology and gene expression profiles over several passages. SHPCs in MEF co-culture metabolize acetam...
ORGANISM(S): Homo sapiens 
2020-09-11 | GSE157791 | GEO
We found that the transplantation of Thy1+ cells transiently increased the liver mass by expanding resident small hepatocy-like progenitor cells(SHPCs). We used microarrays to detail the gene expression of receptors of growth factors of SHPCs clusters with and without Thy1+ cells transplantation. SH...
ORGANISM(S): Rattus norvegicus 
We found that the transplantation of bone marrow mesenchymal cells (BM-MCs) transiently increased the liver mass by expanding resident small hepatocy-like progenitor cells (SHPCs). We used microarrays to detail the gene expression of SHPCs clusters with and without BM-MCs transplantation.
ORGANISM(S): Rattus norvegicus 
2020-07-09 | GSE154022 | GEO
We found that the transplantation of Thy1+ cells transiently increased the liver mass by expanding resident small hepatocy-like progenitor cells(SHPCs). We used microarrays to detail the gene expression of receptors of growth factors of SHPCs clusters with and without Thy1+ cells transplantation.
ORGANISM(S): Rattus norvegicus 
2016-08-14 | GSE85577 | GEO
Extracellular vesicles containing miR-146a-5p activate hepatocytic progenitor cells in regenerating retrorsin-treated rat livers
Expression of rat hepatocytic progenitor cells with and without hepatic Thy1-positive cells in retrorsine/partial hepatectomy treated rats models.
Co-culture with mouse embryonic fibroblasts improves maintenance of metabolic function of human small hepatocyte progenitor cells
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