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The multi-domain deubiquitinase USP15 regulates diverse eukaryotic processes and has been implicated in numerous diseases. We developed ubiquitin variants (UbVs) that targeted either the catalytic domain or each of three adaptor domains in USP15, including the N-terminal DUSP domain. Taking advantag...
ORGANISM(S): Homo sapiens (Human) 
2019-01-16 | PXD011840 | Pride
Structure-based E2 enzyme variants (E2Vs) were used to create biotinylated activity-based probes use as handles for affinity purification-mass spectrometry to identify interacting E3s.
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD068594 | Pride
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