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TranscriptomicsTranscription profiling of peripheral blood leukocyte subsets in autoimmune/autoinflammatory disease patients and healthy controls
Gene expression microarray profiling was performed on peripheral blood leukocyte subsets (CD4+ T cells, CD14+ monocytes, and CD16+ neutrophils) from healthy controls and patients with flaring autoimmune disease.
ORGANISM(S): Homo sapiens 
2014-08-31 | E-MTAB-2452 | biostudies-arrayexpress
ProteomicsSubfamily C7 Raf-like kinases MRK1, RAF26, and RAF39 regulate immune homeostasis and stomatal opening in Arabidopsis thaliana
The calcium-dependent protein kinase CPK28 is a regulator of immune homeostasis in multiple plant species. Here, we used a proteomics approach to uncover CPK28-associated proteins. We found that CPK28 associates with subfamily C7 Raf-like kinases MRK1, RAF26, and RAF39, and trans-phosphorylates RAF2...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2024-09-30 | PXD052803 | Pride
Quantitative proteomics 
UnknownAdvances in ultrasound-activated nano-sonosensitizers for cancer treatment: a systematic review and meta-analysis.
Not available
S-EPMC12925597 | biostudies-literature
ProteomicsComplex I Inhibition combined with TLR Activation in the Breast Tumor Microenvironment Educates Cytotoxic Neutrophils
Neutrophils have emerged as diverse regulators of tissue states, displaying functions in both the resolution and promotion of tissue inflammation. While neutrophils have widely been associated with tumor promotion, immune suppression, and poor patient outcome, we provide evidence to support direct t...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-04 | PXD054085 | Pride
Breast cancer Secretory granules Complex i inhibition Tlr receptors Nf-kb signaling Oxidative stress Neutrophils 
UnknownSelective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma.
Not available
S-EPMC6905485 | biostudies-literature
ProteomicsCatalytically inactive subgroup VIII receptor-like cytoplasmic kinases regulate the immune-triggered oxidative burst in Arabidopsis thaliana
Protein kinases are key components of multiple cell signaling pathways. Several protein kinases of the receptor-like cytoplasmic kinase (RLCK) family have demonstrated roles in immune and developmental signaling across various plant species, making them a family of interest in the study of phosphory...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-05-07 | PXD052679 | Pride
Arabidopsis thaliana Protein kinase 
UnknownTNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis.
Not available
S-EPMC4268493 | biostudies-literature
UnknownThe TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.
Not available
S-EPMC5112176 | biostudies-literature
UnknownTwo phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
Not available
S-EPMC4159618 | biostudies-literature
UnknownDeciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries.
Not available
S-EPMC10094749 | biostudies-literature
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