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TranscriptomicsRegulation of Transcription Termination by Glucosylated Hydroxymethyluracil, Base J, in L. major and T. brucei
Base J, β-D-glucosyl-hydroxymethyluracil, is an epigenetic modification of thymine in the nuclear DNA of flagellated protozoa of the order Kinetoplastida. J is enriched at sites involved in RNA Polymerase (RNAP) II initiation and termination. We have previously demonstrated a role of J in regulating...
ORGANISM(S): Trypanosoma brucei 
2015-05-18 | E-GEOD-57621 | biostudies-arrayexpress
TranscriptomicsBase J represses genes at the end of polycistronic gene clusters in Leishmania major by promoting RNAP II termination
Base J and H3.V promote RNA Polymerase (RNAP) II termination within polycistronic gene clusters in the kinetoplastid species Trypanosoma brucei. Although base J has been shown to promote RNAP II termination in the related kinetoplastid species Leishmania major and Leishmania tarentolae, the role of ...
ORGANISM(S): Leishmania major 
2016-07-20 | E-GEOD-77632 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Arabidopsis guard cells and mesophyll cells in response to ABA treatment
Transcriptional profiling of guard cells and mesophyll cells in response to ABA treatment
ORGANISM(S): Arabidopsis thaliana 
2008-02-02 | E-MEXP-1443 | biostudies-arrayexpress
UnknownA second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Not available
S-EPMC10823175 | biostudies-literature
UnknownQuality of life and mental health in children and adolescents during the first year of the COVID-19 pandemic: results of a two-wave nationwide population-based study.
Not available
S-EPMC8506100 | biostudies-literature
UnknownChild and Adolescent Mental Health During the COVID-19 Pandemic: Results of the Three-Wave Longitudinal COPSY Study.
Not available
S-EPMC9386895 | biostudies-literature
TranscriptomicsThe prognostic ease and difficulty of invasive breast carcinoma
Breast carcinoma (BC) have been extensively profiled by high-throughput technologies for over a decade, and broadly speaking, these studies can be grouped into those that seek to identify patient subtypes (studies of heterogeneity) or those that seek to identify gene signatures with prognostic or pr...
ORGANISM(S): Homo sapiens 
2014-10-08 | E-GEOD-58644 | biostudies-arrayexpress
UnknownCell motility and migration as determinants of stem cell efficacy.
Not available
S-EPMC7494685 | biostudies-literature
UnknownExamining the Occurrence and Clinical Impact of Difficult Experiences that Emerge during a Mindfulness-Based Intervention among Individuals at High-Risk of Suicide.
Not available
S-EPMC11931679 | biostudies-literature
UnknownSelective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma.
Not available
S-EPMC6905485 | biostudies-literature
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