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UnknownPyruvate kinase splice variants in fibroblasts influence cardiac remodeling after myocardial infarction in male mice.
Not available
S-EPMC12344556 | biostudies-literature
ProteomicsExploiting TGF-β-mediated Stromal Programming in Homologous Recombination-Deficient Pancreatic Cancer
The tumor microenvironment (TME) actively contributes to pancreatic ductal adenocarcinoma (PDAC) pathogenesis via a dynamic bidirectional tumor–stroma dialog. Here, we show that homologous recombination-defective (HRD) neoplastic epithelium reprograms its TME in a genotype-specific manner to promote...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-27 | PXD042750 | Pride
P53 Atm Tumor–stroma crosstalk Pancreatic ductal adenocarcinoma Personalized medicine Cancer-associated fibroblasts Tumor microenvironment 
TranscriptomicsPitx1 Haploinsufficiency Causes Clubfoot in Humans and Mice
To identify genes regulated by Pitx1 during early hindlimb development, we compared gene expression differences between hindlimb buds from E12.5 Pitx1+/+ and Pitx1-/- mice on the Illumina MouseRef-8 expression Bead Chip. Genes involved in muscle development GeneGO processes were highly enriched in ...
ORGANISM(S): Mus musculus 
2011-11-21 | E-GEOD-27363 | biostudies-arrayexpress
ProteomicsUrinary Proteome of Chronic Kidney Disease of Unknown Etiology (CKDu)
2 mL of preserved urine samples were precipitated overnight with 5 mL of ice-cold acetone, pellets were washed 70% acetone resuspended in 5% SDS followed by trypsin digestion of up to 100 ugs of each sample using an S-trap. One-third of tryptic peptides were microflow LC-MS/MS using an ACQUITY UPLC ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-10-11 | MSV000090513 | MassIVE
TranscriptomicsA sentinel function for teat tissues in dairy cows: dominant innate immune response elements define response to mastitis
Mastitis remains one of the most prevalent and costly diseases impacting the dairy industry worldwide. Escherichia coli is an environmental bacterium that frequently causes intramammary infections, the outcome of which depends on the capacity of the host to recognize and clear the bacterial pathogen...
ORGANISM(S): Bos taurus 
2009-08-18 | E-GEOD-15441 | biostudies-arrayexpress
UnknownIL-27 maintains cytotoxic Ly6C+ gamma delta T cells that arise from immature precursors
Not available
S-SCDT-10_1038-S44318-024-00133-1 | biostudies-other
UnknownCommon breast cancer susceptibility loci are associated with triple-negative breast cancer.
Not available
S-EPMC3327299 | biostudies-literature
UnknownEffects of a Lifestyle Intervention to Prevent Deterioration in Glycemic Status Among South Asian Women With Recent Gestational Diabetes: A Randomized Clinical Trial.
Not available
S-EPMC8892226 | biostudies-literature
UnknownSafety and Efficacy of Combination SARS-CoV-2 Neutralizing Monoclonal Antibodies Amubarvimab Plus Romlusevimab in Nonhospitalized Patients With COVID-19.
Not available
S-EPMC10150320 | biostudies-literature
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