Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...
In arthropods, hemolymph carries immune cells and solubilizes and transport nutrients, hormones, and other molecules that are involved in diverse physiological processes including immunity, metabolism and reproduction. However, despite such physiological importance, little is known about its composi...
Bacteria in polymicrobial communities engage in complex interactions, including interbacterial antagonism. In Chromobacterium violaceum, the Type VI Secretion System (T6SS) serves as a critical antibacterial weapon, but the full set of effectors delivered by this system remains not yet completely de...
While cellular transcripts encode rich information that provide key features to understand the molecular basis of snake venom variation, their presence/ abundance does not necessary imply/correlate in the translation of a functional (protein) product. In this study we carried out an analysis of the ...
Cellular communication strongly relies on the secretion of soluble mediators that, in general, interact with cell surface receptors and enable biological responses in a proper timescale for signaling processes to occur. Therefore, the study of secreted proteins (the secretome) from normal cells and ...
Gene expression profiling of ErbB2-engineered MCF10A and WT cells in 2D and 3D culture Gene expression profiling of ErbB2-engineered MCF10A and WT cells, 2D and 3D culture, 5 or 6 replicates
Overexpression in IL6 in MCF10A vs. WT, MCF10A.ErbB2* with/without shRNA targeting STAT3 Overexpression in IL6 in MCF10A vs. WT, MCF10A.ErbB* with/without shSTAT3, duplicates, two STAT3 shRNAs
