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TranscriptomicsTranscription profiling of S. cerevisiae (budding yeast) mutants reveals Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and programmed cell death
Changes in the transcriptome of Isc1p deficient mutants. The inositolphosphosphingolipid phospholipase C (Isc1p) of Saccharomyces cerevisiae belongs to the family of neutral sphingomyelinases that generates the bioactive sphingolipid ceramide. In this work the role of Isc1p in oxidative stress resis...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-05 | E-MEXP-1136 | biostudies-arrayexpress
TranscriptomicsiPSC-derived cardiomyocytes at the single-cell level
Currently, cardiomyocytes differentiated from human induced pluripotent stem cells (iPSCs) are routinely generated for disease research and drug development as an alternative to animal models. To assess which cell types are present at day 30 of differentiation, we conducted single-cell RNA sequencin...
ORGANISM(S): Homo sapiens 
2025-02-28 | E-MTAB-13850 | biostudies-arrayexpress
TranscriptomicsThe transcriptome of human iPSC-derived cardiomyocytes
Currently, cardiomyocytes differentiated from human induced pluripotent stem cells (iPSCs) are routinely generated for disease research and drug development as an alternative to animal models. Although iPSC-derived cardiomyocytes (iPSC-CMs) are generally assumed to resemble myocytes in the fetal hea...
ORGANISM(S): Homo sapiens 
2025-03-30 | E-MTAB-13757 | biostudies-arrayexpress
MetabolomicsGut microbiota within-host evolution enforces colonization resistance against enteric infection

Limited resource availability in the gut promotes competitive interactions between bacteria, which drive adaptive within-host evolution. While the role of bacterial adaptive evolution of bacterial communities has been extensively studied, its functional implications for host physiology remain unk...

2026-08-03 | MTBLS10327 | MetaboLights
UnknownCharacteristics, management, and outcomes of patients with left-sided infective endocarditis complicated by heart failure: a substudy of the ESC-EORP EURO-ENDO (European infective endocarditis) registry.
Not available
S-EPMC9543970 | biostudies-literature
UnknownPrevalence and mortality associated with multidrug-resistant infections in adult intensive care units in Argentina (PREV-AR).
Not available
S-EPMC11881575 | biostudies-literature
UnknownA core outcome set for locoregional treatment reporting in neoadjuvant systemic breast cancer treatment trials.
Not available
S-EPMC12568921 | biostudies-literature
UnknownMortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study.
Not available
S-EPMC8314066 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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