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ProteomicsMeningeal γδ T cells producing IL-17 control synaptic plasticity and cognitive behaviour
The conventional notion of “immune privilege” of the brain has been revised to accommodate its infiltration, at steady state, by immune cells that participate in normal neurophysiology (Louveau, Trends Immunol 2015; Kipnis science 2016; Filiano, Nat Rev Neurosciences 2017). Surprisingly, such neuroi...
ORGANISM(S): Mus musculus (Mouse) 
2019-10-16 | PXD007574 | Pride
Swath Il-17 Γδ t cells 
ProteomicsProteomics of high density lipoprotein subfractions in type 1 diabetes mellitus and controls
Toyoshima MTK. Proteomics and functionality of high-density lipoprotein subfractions and subclinical cardiovascular disease in type 1 diabetes mellitus. Faculdade de Medicina, Universidade de Sao Paulo 2021.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-08-13 | MSV000087986 | MassIVE
GenomicsIntegration of epigenetic and transcriptional mechanisms governs functional commitment versus plasticity of gd T cell subsets
gd T cells are major innate sources of interleukin-17 (IL-17) and interferon-g (IFN-g), which are differentially produced by two thymically-derived subsets segregated on CD27 expression. However, the molecular mechanisms that program the functional differentiation of gd cells remain incompletely und...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-42098 | biostudies-arrayexpress
TranscriptomicsTCR signal strength controls thymic differentiation of discrete proinflammatory γδT cell subsetsistinct TCR signal strength requirements in the thymus
The murine thymus produces discrete γδ T cell subsets making either IFN-γ or IL-17, but the role of the TCR in this developmental process remains controversial. Here we generated a non-transgenic and polyclonal model of reduced TCR expression and signal strength selectively on γδ T cells. Mice ...
ORGANISM(S): Mus musculus 
2016-03-29 | E-GEOD-71637 | biostudies-arrayexpress
UnknownHydroxychloroquine with or without Azithromycin in Mild-to-Moderate Covid-19.
Not available
S-EPMC7397242 | biostudies-literature
UnknownA New Natural Language Processing-Inspired Methodology (Detection, Initial Characterization, and Semantic Characterization) to Investigate Temporal Shifts (Drifts) in Health Care Data: Quantitative Study.
Not available
S-EPMC11555458 | biostudies-literature
UnknownKetamine, Etomidate, and Mortality in Emergency Department Intubations.
Not available
S-EPMC12706683 | biostudies-literature
TranscriptomicsTumor exosome integrins determine organotropic metastasis
Stephen Paget first proposed, in 1889, that organ distribution of metastases is a non-random event, yet metastatic organotropism remains one of the greatest mysteries in cancer biology. Here, we demonstrate that exosomes released by lung-, liver- and brain-tropic tumor cells fuse preferentially with...
ORGANISM(S): Homo sapiens 
2015-06-17 | E-GEOD-68919 | biostudies-arrayexpress
UnknownSeverity of cardiovascular disease outcomes among patients with HIV is related to markers of inflammation and coagulation.
Not available
S-EPMC4309077 | biostudies-literature
UnknownABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores.
Not available
S-EPMC8302820 | biostudies-literature
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