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TranscriptomicsProtein coding gene expression profile of dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib
Dasatinib has demonstrated efficacy in patients with chronic-phase chronic myeloid leukemia (CML) who had resistance or intolerance to imatinib. However, some patients also develop resistance or intolerance to dasatinib. To identify potential molecular pathways involved in primary resistance to dasa...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-33224 | biostudies-arrayexpress
TranscriptomicsNoncoding RNA expression profile of dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib
Dasatinib has demonstrated efficacy in patients with chronic-phase chronic myeloid leukemia (CML) who had resistance or intolerance to imatinib. However, some patients also develop resistance or intolerance to dasatinib. To identify potential molecular pathways involved in primary resistance to dasa...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-33288 | biostudies-arrayexpress
TranscriptomicsGene expression signatures of dasatinib-treated chronic myeloid leukemia patients with resistance to imatinib
Dasatinib has demonstrated efficacy in patients with chronic-phase chronic myeloid leukemia (CML) who had resistance or intolerance to imatinib. However, some patients also develop resistance or intolerance to dasatinib. To identify potential molecular pathways involved in primary resistance to dasa...
ORGANISM(S): Homo sapiens 
2013-07-31 | E-GEOD-33290 | biostudies-arrayexpress
GenomicsProcardis study on novel susceptibility genes for coronary artery disease (CAD)
An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood. METHODS: We used a novel gene c...
EGAS00000000055 | EGA
GenomicsEGAD00000000028
Aggregate results from a GWAS study on 3352 cases abd 3145 controls
EGAD00000000028 | EGA
TranscriptomicsThe Stockholm Atherosclerosis Gene Expression (STAGE) study: Global Gene Expression data from coronary and carotid artery disease patients
Tissue samples have been isolated during corornary artery by-pass grafting (CABG)surgery from the atheroscelrotic arterial wall (AAW, aortic root puncture for proxmal ligation of by-pass vessel), non-atherosclertoci arterial wall (NAAW, distal part of mammary artery used a graft for LAD), liver, sk...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-40231 | biostudies-arrayexpress
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