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TranscriptomicsMicroRNA signatures predict Estrogen receptor, Progesterone receptor and HER2/neu receptor status in Breast Cancer
Breast cancer is a heterogeneous disease encompassing a number of phenotypically diverse tumours. Expression levels of the estrogen, progesterone and HER2/neu receptors which characterise clinically distinct breast tumors have been shown to change during disease progression and in response to system...
ORGANISM(S): Homo sapiens 
2010-05-18 | E-GEOD-15885 | biostudies-arrayexpress
TranscriptomicsThe TAB1-p38α complex aggravates myocardial injury and can be targeted by small molecules
There is considerable evidence that inhibition of p38α mitogen-activated protein kinase diminishes cardiac damage during myocardial ischemia. During myocardial ischemia p38α interacts with TAB1, a scaffold protein, which promotes p38α autoactivation; active p38α (pp38α) then trans-phosphorylates TAB...
ORGANISM(S): Mus musculus 
2018-08-27 | E-MTAB-6460 | biostudies-arrayexpress
TranscriptomicsDNA methylation analysis of phaeochromocytoma, paraganglioma and normal adrenal medulla samples
Illumina Infinium MethylationEPIC BeadChip array files from phaeochromocytoma, paraganglioma tumours of different genotypes and normal adrenal medulla control samples. This is the first study using high-resolution MethylationEPIC arrays and also includes a large number of Cluster 1 tumours (n=16) wh...
ORGANISM(S): Homo sapiens 
2023-12-21 | E-MTAB-13433 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation genome wide binding site identification in yeast
Genome Wide Location: binding site identification
ORGANISM(S): Saccharomyces cerevisiae 
2013-01-30 | E-WMIT-1 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Photobacterium profundum SS9 strain cells grown at two different pressure conditions 45 MPa and at 28 MPa
P. profundum SS9 strain cells were grown at two different pressure conditions 45 MPa and at 28 MPa. RNA extracted from the two different cultures was labelled with Cy5 and Cy3 and competitively hybridized on the same slide.
ORGANISM(S): Photobacterium profundum 
2006-05-24 | E-MEXP-374 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Phytobacterium profundum SS9 strain cells grown at two different temperatures 4?C and 16?C
P. profundum SS9 strain cells were grown at two different temperatures 4°C and 16°C. RNA extracted from the two different cultures was labelled with Cy5 and Cy3 and competitively hybridized on the same slide.
ORGANISM(S): Photobacterium profundum 
2006-04-30 | E-MEXP-348 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human CD4 regulatory T cells that express either CD45RA or CD45RO
CD4 T cells taken from 6 donors were sorted into CD25hi CD45RA+ (na�ve Treg), CD25hi CD45RO+ (memory Treg), CD25- CD45RA+ (na�ve responder) and CD25- CD45RO+ (memory responder) populations.

RNA was extracted (Ambion RNAqueous), amplified (SMART), labelled with cy3, mixed with cy5 labelle...
ORGANISM(S): Homo sapiens 
2009-10-05 | E-MEXP-2372 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Phytobacterium profundum SS9 strain cells grown at two different pressure conditions 0.1 MPa and at 28 MPa
P. profundum SS9 strain cells were grown at two different pressure conditions 0.1 MPa and at 28 MPa. RNA extracted from the two different cultures was labelled with Cy5 and Cy3 and competitively hybridized on the same slide.
ORGANISM(S): Photobacterium profundum 
2005-07-28 | E-MEXP-210 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation genome wide location analysis of yeast transcriptional regulators under multiple growth conditions
Genomic binding of 203 transcriptional regulatory proteins under various conditions. Hybridizations of fluorescently-labelled immunoprecipitated vs. whole-cell extract samples on S. cerevisiae intergenic arrays.
ORGANISM(S): Saccharomyces cerevisiae 
2004-09-02 | E-WMIT-10 | biostudies-arrayexpress
GenomicsThe ets transcription factor ELF5 suppresses the estrogen sensitive phenotype and contributes to antiestrogen resistance in luminal breast cancer. [human ChIP-Seq]
The ets transcription factor ELF5 specifies the differentiation of mammary progenitor cells to establish the milk-secreting lineage. ER- and poor prognosis basal breast cancers arise from this progenitor cell and these cancers express high levels of Elf5. Knockdown of ELF5 expression in basal breast...
ORGANISM(S): Homo sapiens 
2012-12-27 | E-GEOD-31216 | biostudies-arrayexpress
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