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Unknown,Transcriptomics,Genomics,Proteomics

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Chromatin immunoprecipitation genome wide binding site identification in yeast

ABSTRACT: Genome Wide Location: binding site identification

INSTRUMENT(S): vortex

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Richard Young

PROVIDER: E-WMIT-1 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptional regulatory networks in Saccharomyces cerevisiae.

Lee Tong Ihn TI Rinaldi Nicola J NJ Robert François F Odom Duncan T DT Bar-Joseph Ziv Z Gerber Georg K GK Hannett Nancy M NM Harbison Christopher T CT Thompson Craig M CM Simon Itamar I Zeitlinger Julia J Jennings Ezra G EG Murray Heather L HL Gordon D Benjamin DB Ren Bing B Wyrick John J JJ Tagne Jean-Bosco JB Volkert Thomas L TL Fraenkel Ernest E Gifford David K DK Young Richard A RA

Science (New York, N.Y.) 20021001 5594

We have determined how most of the transcriptional regulators encoded in the eukaryote Saccharomyces cerevisiae associate with genes across the genome in living cells. Just as maps of metabolic networks describe the potential pathways that may be used by a cell to accomplish metabolic processes, this network of regulator-gene interactions describes potential pathways yeast cells can use to regulate global gene expression programs. We use this information to identify network motifs, the simplest ...[more]

PMID: 12399584

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