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TranscriptomicsRNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer
The translational control of oncoprotein expression is implicated in many cancers. Here we report an eIF4A/DDX2 RNA helicase-dependent mechanism of translational control that contributes to oncogenesis and underlies the anticancer effects of Silvestrol and related compounds. For example, eIF4A promo...
ORGANISM(S): Homo sapiens 
2014-07-27 | E-GEOD-56887 | biostudies-arrayexpress
ProteomicsPolysome pellet digests - identification of proteins in polysome pellet with and without silvestrol treatment
identification of proteins in polysome pellet with and without silvestrol treatment
ORGANISM(S): Homo sapiens (Human) 
2014-09-16 | PXD001310 | Pride
Polysome Silvestrol 
GenomicsExpression data from A375 melanoma cells treated with Interferon-gamma and silvestrol
Expression data from A375 melanoma cells treated with Interferon-gamma and silvestrol
PRJNA485934 | ENA
UnknownSilvestrol Inhibits Chikungunya Virus Replication.
Not available
S-EPMC6266838 | biostudies-literature
TranscriptomicsExpression data from A375 melanoma cells treated with Interferon-gamma and silvestrol
Identify transcriptionnaly and translation regulated RNA by Interferon-gamma and silvestrol
ORGANISM(S): Homo sapiens 
2018-11-23 | GSE118521 | GEO
UnknownInhibition of Zika Virus Replication by Silvestrol.
Not available
S-EPMC5923443 | biostudies-literature
UnknownAntitumor activity and mechanism of action of the cyclopenta[b]benzofuran, silvestrol.
Not available
S-EPMC2671147 | biostudies-literature
UnknownIn Vitro Safety, Off-Target and Bioavailability Profile of the Antiviral Compound Silvestrol.
Not available
S-EPMC9502993 | biostudies-literature
UnknownNatural antiviral compound silvestrol modulates human monocyte-derived macrophages and dendritic cells.
Not available
S-EPMC7267175 | biostudies-literature
UnknownBroad-spectrum antiviral activity of the eIF4A inhibitor silvestrol against corona- and picornaviruses.
Not available
S-EPMC7113723 | biostudies-literature
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