Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold tremendous promise for in vitro modeling 2 to assess native myocardial function and disease mechanisms as well as testing drug safety and efficacy. However, 3 current iPSC-CMs are functionally immature, resembling in vivo CMs of fe...
Differential transcriptional profiles from endothelial cells isolated from opposite sides of aortic valves from healthy adult male pigs (N=8, from slaughterhouse). Samples were hybridized to a human array and paired by animal.
The overall purpose of this study was to demonstrate the feasibility of producing haplotype-phased whole genome sequence data from a fetus using free fetal DNA isolated from maternal plasma collected during the first half of gestation.
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...