Sort   by:  
 Page size 
TranscriptomicsExpression analysis of C. elegans wild-type N2 and rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutants
Investigation of whole genome gene expression level changes in C. elegans rsks-1, daf-2, daf-2 rsks-1 and daf-16; daf-2 rsks-1 mutant compared to the wild-type N2 strain. The mutants have altered longevity phenotypes. The mutants analyzed in this study are further described in Di Chen, Patrick Wai-...
ORGANISM(S): Caenorhabditis elegans 
2013-11-14 | E-GEOD-52340 | biostudies-arrayexpress
TranscriptomicsscRNA-seq analysis of enriched CD4+ T cells from lung tissues after single or combined AIT treatment strategies with AhR agonist 10-Cl-BBQ in a murine model of OVA-induced allergic airway inflammation (AAI)
Allergen-specific immunotherapy (AIT) is able to restore immune tolerance to allergens in allergic patients. However, some patients do not or only poorly respond to current treatment protocols. Therefore, there is a need for deeper mechanistic insights and further improvement of treatment strategies...
ORGANISM(S): Mus musculus 
2024-05-06 | E-MTAB-14030 | biostudies-arrayexpress
Proteomics,MultiomicsTranslational regulation contributes to the secretory response of chondrocytic cells following exposure to Interleukin-1B
Chondrocytes undergo changes to their protein translational capacity during osteoarthritis progression, but a study of how disease-relevant signals affect chondrocyte protein translation at the transcriptome level has not previously been performed. In this study we describe how the inflammatory cyto...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-07-17 | MSV000084104 | MassIVE
TranscriptomicsRibosome profiling of chondrocytic cell line SW1353 following exposure to IL-1B
Osteoarthritis is a chronic disease characterised by the loss of articular cartilage in synovial joints through a process of extracellular matrix destruction that is strongly associated with inflammatory stimuli. Chondrocytes undergo changes to their protein translation capacity during osteoarthriti...
ORGANISM(S): Homo sapiens 
2019-07-12 | E-MTAB-7466 | biostudies-arrayexpress
UnknownRisk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.
Not available
S-EPMC4463475 | biostudies-literature
ProteomicsA Global Ligandability Map of Tryptoline Butynamide Stereoprobes Identifies Covalent Inhibitors of the Actin Maturation Protease ACTMAP
Covalent chemistry coupled with activity-based protein profiling (ABPP) offers a versatile approach for small-molecule ligand discovery in native biological contexts. The covalent ligandability maps generated by ABPP that target cysteine have frequently leveraged the acrylamide as a reactive group d...
ORGANISM(S): Homo sapiens (Human) 
2026-05-20 | PXD074619 | Pride
TranscriptomicsTranscription profiling of Lgr6+ keratinocyte populations in the epidermis and hair follicle
RNA sequencing was performed on sorted populations of Lgr6-positive and Lgr6-negative keratinocytes from the interfollicular epidermis and the hair follicle/sebaceous gland, in order to determine the compartment-specific expression signatures of Lgr6+ progenitor cells.
ORGANISM(S): Mus musculus 
2015-10-22 | E-MTAB-3533 | biostudies-arrayexpress
UnknownA Notch/STAT3-driven Blimp-1/c-Maf-dependent molecular switch induces IL-10 expression in human CD4+ T cells and is defective in Crohn´s disease patients.
Not available
S-EPMC9038525 | biostudies-literature
TranscriptomicsEngineering acetyl-CoA supply: Functional expression of a bacterial pyruvate-dehydrogenase complex in the cytosol of Saccharomyces cerevisiae
The energetic (ATP) cost of biochemical pathways critically determines the maximum yield of metabolites of vital or commercial relevance. Cytosolic acetyl-CoA is a key precursor for biosynthesis in eukaryotes and for many industrially relevant product pathways that have been introduced into Saccharo...
ORGANISM(S): Saccharomyces cerevisiae 
2014-11-04 | E-GEOD-59814 | biostudies-arrayexpress
ProteomicsPROTOMAP analysis of Human Cartoid Plaques
Human cartoid plaques were removed in operating room and placed in tube with PBS.Plaques were then analyzed for presence of rupture. The ulcerated lesicon was then excised and subjected to protein extraction. Areas of stable plaque tissue was then excised as a control.
ORGANISM(S): Homo sapiens (Human) 
2020-08-10 | PXD020405 | Pride
Human Plaques Protomap 
Sort   by:  
 Page size